Grant: UNIVERSITY OF SOUTHERN CALIFORNIA
Primary Recipient
UNIVERSITY OF SOUTHERN CALIFORNIA
Amount
$450,009.00
Award Date
7/23/2009
Administering Agency
Health and Human Services, Department of / National Institutes of Health
CDFA Number
93.701
CDFA Program Title
Trans-NIH Recovery Act Research Support
Description
Our central hypothesis is that the interaction between HIV-1 integrase (IN) and the cellular co-factor LEDGF/p75 is important for efficient viral replication. We further hypothesize that inhibitors of this interaction have antiviral activity, a low chance