Primary Recipient

UNIVERSITY OF NEBRASKA

Amount

$226,931.00

Award Date

9/30/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

The genes of Runx1 and its heterodimeric partner Cbf? are disrupted by chromosomal translocations, inversions and point mutations in over 30% of human leukemias. Ets1 is amplified and rearranged in leukemia and lymphoma, and elevated Ets1 expression has