Primary Recipient

MARQUETTE UNIVERSITY

Amount

$218,337.00

Award Date

8/12/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

Because enzymes often bind two substrates cooperatively, it may be difficult to design inhibitors that span both binding sites, using fragment assembly methods. While fragment assembly strategies exploiting a single binding site have yielded many high aff