Primary Recipient

TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

Amount

$621,030.00

Award Date

5/05/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

Tumor development is a multi-step process that depends upon the successive activation of oncogenes and inactivation of tumor suppressor genes. p53 is mutated in about 50% of human tumors and the p53 protein is known as a guardian of the genome because of