Primary Recipient

UNIVERSITY OF IOWA, THE

Amount

$498,000.00

Award Date

7/16/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

Rituximab is widely used as a therapy for B cell malignancies. Despite its certain clinical value, the mechanisms responsible for the clinical anti-tumor effect of rituximab and other monoclonal antibodies (mAb) are unclear. Both antibody-dependent cellul