Primary Recipient

BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE

Amount

$166,000.00

Award Date

9/29/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

Our data from the parent K99/R00 indicated that the TGF-β-induced TACE (TNF-α converting enzyme) activation/translocation plays a key role in the growth and invasiveness of HER2-overespressing breast cancer cells and mediates cell resistance to