Primary Recipient

FRED HUTCHINSON CANCER RESEARCH CENTER

Amount

$298,300.00

Award Date

8/13/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

Our goal is to find inhibitors of the E. coli RecBCD enzyme, one of the subjects of the parent grant. Inhibitors would allow us to study in greater detail the mechanism of this complex enzyme required for repair of DNA double-strand breaks; we could use