Primary Recipient

SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH

Amount

$786,840.00

Award Date

6/04/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

In collaboration with the structural biologist Dr. Hao Wu, we solved the co-crystal structure of one of the compounds in complex with caspase-7. The crystal structure revealed the allosteric nature of the binding and also provides guidance for future med