Primary Recipient

BENAROYA RESEARCH INSTITUTE AT VIRGINIA MASON

Amount

$189,956.00

Award Date

6/28/2010

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

Our currently funded grant explores TREM-2 and DAP12 inhibition of Toll-like receptor signaling in macrophages. Aim 2 of this grant explores the signaling mechanism by which this inhibition occurs, mainly focusing on src family kinases and MAPK pathways.