Primary Recipient

YALE UNIVERSITY

Amount

$870,314.00

Award Date

9/15/2009

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

BCL-xL is the major anti-cell death BCL-2 family member expressed in brain, and understanding its function is key to designing strategies for neuroprotection. In this application, we will attempt to prove that inhibition of BCL-xL or down regulation of ex