Primary Recipient

BENAROYA RESEARCH INSTITUTE AT VIRGINIA MASON

Amount

$389,663.00

Award Date

9/30/2010

Administering Agency

Health and Human Services, Department of / National Institutes of Health

CDFA Number

93.701

CDFA Program Title

Trans-NIH Recovery Act Research Support

Description

Defective regulation of the immune system is central to the development and progression of T1D. Multiple mechanisms are responsible for maintaining tolerance, including regulatory T cells. Our work has identified that two mechanisms by which Treg fail