Recovery Tracker

How Much Stimulus Funding is Going to Your County?

Adams County, Colo., funds by Health and Human Services, Department of

Listing $76,064,376.12 in stimulus funds from Health and Human Services, Department of for Adams

Note: For some programs where states do not report where money will be distributed across the state, we do not have the allocation for individual counties. Those programs include: Medicaid, unemployment benefits and food stamps. Those amounts are included in the totals for where the state agency receiving that money is located.

Amount refers to both the amount of stimulus funding going toward the project and the face value of the loan.

Recipient Amount Description Federal Dept./Agency Date
REGENTS OF THE UNIVERSITY OF COLORADO, THE $6,061,634 Recovery Act Comparative Effectiveness Research - AHRQ The overall goals of this project are to enhance the capacity and capability of a safety net focused distributed research network to conduct prospective comparative effectiveness research via a multi-setting, multi-state organization. The Scalabl... Show more
This spending item is part of a $8,309,543 allocation. See details
Agency for Healthcare Research and Quality 9/28/2010
ADAMS, COUNTY OF $2,830,652 ARRA Child Care and Development Block Grant The CCDF ARRA funds will be used to provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $24,312,305 allocation. See details
Administration for Children and Families 4/09/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $2,622,186 ARRA - Health Information Technology Professionals in Health Care The Colorado Health Information Education Collaborative's (HITEC) goal is to expand and integrate existing educational programs at the University of Colorado Denver to prepare a workforce of 122 professionals that are capable of servin... Show more Health and Human Services, Department of 4/02/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $2,271,441 Trans-NIH Recovery Act Research Support Our application belongs to the theme, 'Translating Basic Science Discoveries into New and Better Treatments'. The goal of the project is to develop the first selective adenosine monophosphate deaminase- 2 (AMPD2) inhibitor, which we believe will offer an National Institutes of Health 9/30/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $1,817,338 Trans-NIH Recovery Act Research Support Palliative care, a relatively new subspecialty, needs to build its evidence base supporting clinical practice. The Institute of Medicine has identified palliative care as a comparative effectiveness research priority, but increased scientific productivity
This spending item is part of a $7,175,320 allocation. See details
National Institutes of Health 9/30/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $1,482,589 Trans-NIH Recovery Act Research Support The major intent of this project is to modify and expand a family weight gain prevention program that has previously been shown to be effective. Our previous America On the Move (AOM) Family Program, which focused on helping families make small changes in National Institutes of Health 8/31/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $1,461,788 Trans-NIH Recovery Act Research Support The University of Colorado Cancer Center (UCCC) is the only NCI-designated comprehensive Cancer Center in the Rocky Mountain region - an area with a population of approximately eight million people. The goals are to reduce the cancer burden by: 1) conduct National Institutes of Health 9/28/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $1,402,278 Recovery Act Comparative Effectiveness Research - AHRQ The Colorado Comparative Effectiveness Research (CER) and Safety K12 Scholars Program will be a national and regional resource for research and training in health care and CER, and the hub for CER in the Rocky Mountain Region. We will develop a n... Show more
This spending item is part of a $1,545,460 allocation. See details
Agency for Healthcare Research and Quality 7/01/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $1,346,247 Trans-NIH Recovery Act Research Support Chronic lung diseases represent a broad spectrum of chronic fibrosing/inflammatory lung conditions that are for the most part poorly responsive to treatment and often fatal. COPD/emphysema is the fourth leading cause of death in the United States and the
This spending item is part of a $9,746,871 allocation. See details
National Institutes of Health 9/25/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $1,334,969 Trans-NIH Recovery Act Research Support American Indians and Alaska Natives (AI/ANs) are at increased risk for Type 2 diabetes when compared to other Americans, a gap that continues to widen. Cardiovascular disease (CVD) has become the number one cause of death among AI/ANs, is now more common National Institutes of Health 9/28/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $1,328,025 Trans-NIH Recovery Act Research Support Acute respiratory failure is a heterogeneous disorder that results in more than 300,000 Americans requiring admission to an intensive care unit for invasive mechanical ventilatory support each year. Though acute respiratory failure is a pulmonary disorder National Institutes of Health 5/22/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $999,999 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (05) Comparative Effectiveness Research (CER) and specific Challenge Topic, 05-LM-103: Improving Compliance of School Children with Immunization Schedules. Despite the immense success of the immunization pro National Institutes of Health 9/30/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $999,868 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (03): Biomarker Discovery and Validation, 03-MH- 101 Biomarkers in mental disorders. The research proposed continues investigation of a new treatment-response biomarker (antipsychotic-biomarker) identified i National Institutes of Health 9/24/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $999,563 Trans-NIH Recovery Act Research Support Bleeding and thrombotic disorders are characterized by significant phenotypic variability. Over the last decade important advances have been made in the understanding of the molecular basis of these disorders; however a large portion of the observed varia National Institutes of Health 9/21/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $992,398 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (15) Translational Science and specific Challenge Topic, 15-EY-101: Protein misfolding in degenerative diseases of the eye. Identifying therapeutic pharmacological agents/drugs that prevent the misfolding/ag National Institutes of Health 9/30/2009
ADAMS, COUNTY OF $975,630 ARRA - Head Start Adams County Head Start has been awarded Expansion funding for an additional 75 children by the Head Start Region VII Office. Expansion funds are being used for: (1) Partnering with three different sites to provide Head Start quality education to these 75 Administration for Children and Families 9/21/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $955,834 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area 03: Biomarker Discovery and Validation and specific Challenge Topic, 03-MH-101 'Biomarkers in mental disorders.' The proposal is designed to develop a biomarker and physiological endophenotype for schizoaffe National Institutes of Health 9/24/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $941,986 Trans-NIH Recovery Act Research Support Chronic lung diseases represent a broad spectrum of chronic fibrosing/inflammatory lung conditions that are for the most part poorly responsive to treatment and often fatal. COPD/emphysema is the fourth leading cause of death in the United States and the
This spending item is part of a $1,654,805 allocation. See details
National Institutes of Health 11/04/2011
REGENTS OF THE UNIVERSITY OF COLORADO, THE $913,423 Trans-NIH Recovery Act Research Support This competitive revision application is in response to NOT-OD-09-058: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications and is for funds to supplement our original R24, The Rodent Gene Array Program (R-GAP). In ou National Institutes of Health 9/25/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $869,165 Trans-NIH Recovery Act Research Support Oral cancer survival has not improved for the past 20 yrs. Recently, cancer stem cell (CSC)- based therapies have shown their potential to control cancer recurrence. However, the lack of in vivo models has hindered attempts to identify markers of oral CSC National Institutes of Health 9/17/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $854,132 Trans-NIH Recovery Act Research Support The goals of this project are: 1) Form a Cardiovascular Risk Reduction Learning Community; 2) Electronically collect and analyze data on trajectories of hypertension and LDL-cholesterol control, antihypertensive and hypolipidemic drug prescription and ful
This spending item is part of a $998,030 allocation. See details
National Institutes of Health 9/30/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $849,987 Trans-NIH Recovery Act Research Support This application addresses the broad Challenge Area (13) Smart Biomaterials - Theranostics and the specific Challenge Topic, 13-DE-102: Dental Resin Composites and Caries. With a majority of the more than 100,000 million dental restorative treatments perf National Institutes of Health 9/17/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $805,866 Trans-NIH Recovery Act Research Support A rate limiting step in the development of therapeutic agents for treating diabetic retinopathy is retinal drug delivery. Although intravitreal injections allow significant drug delivery to the retina, repeated intravitreal injections can lead to endophth National Institutes of Health 8/19/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $788,333 Trans-NIH Recovery Act Research Support The long term goal of this project is to understand the molecular mechanisms of alcohol's actions. Due to its small size and lack of chemical features, alcohol is often considered to be a relatively non-specific drug. Many cellular factors have been ident National Institutes of Health 9/10/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $772,101 Trans-NIH Recovery Act Research Support The following is a revised version of RO1 AG013983-22 entitled B Cells and Autoimmunity, which has been reduced in scope to pursue research that can be accomplished in two years rather than the originally proposed five years. The previous application, whi National Institutes of Health 9/11/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $765,000 Trans-NIH Recovery Act Research Support ADPKD is the most common hereditary kidney disease, affecting 1 in 400 to 1000 individuals and accounting for 4% of end-stage renal disease in the United States and 8-10% in Europe. The condition is characterized by progressive development of kidney cysts National Institutes of Health 9/28/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $747,056 Trans-NIH Recovery Act Research Support This is a multi-PI RO1 grant designed to use multiple mouse genetic models of neural tube defects (NTDs, spina bifida and anencephaly) to investigate genetic factors confering NTD risk. Investigations will study how those gene mutations interact with envi
This spending item is part of a $2,366,335 allocation. See details
National Institutes of Health 8/04/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $746,529 Trans-NIH Recovery Act Research Support The axon's growing tip, the nerve growth cone advances by amoeboid locomotion, a process that involves concerted regulation of the actin cytoskeleton and cell adhesion. Growth cone adhesion is not well understood, but recent data indicate that amyloid pre National Institutes of Health 9/14/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $739,625 Trans-NIH Recovery Act Research Support The goal of this project is to define the function of the basic helix-loop-helix transcription factor Hand2 during mammalian lower jaw development. Our hypothesis is that Hand2 contributes to the development of most lower jaw structures by establishing a National Institutes of Health 7/20/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $739,625 Trans-NIH Recovery Act Research Support The development of the limb relies on reciprocal signaling between celln exists concerning the mechanisms of development to enable the majority of these defects to be detected or prevented pre-natally. An important goal is to develop animal models of cong National Institutes of Health 7/13/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $737,845 Trans-NIH Recovery Act Research Support Two years of support for this project will allow us to perform the experiments proposed in Aims 3 and 4 of the original application. We have been able to complete the bulk of Aims 1 and 2 with support from the American Heart Assoc. This supported our hypo National Institutes of Health 6/30/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $736,271 Trans-NIH Recovery Act Research Support Hepatitis C virus (HCV) is a major health problem affecting approximately 200 million throughout the world. Although new therapies have improved the rates of sustained response, a large proportion of patients (~50%) fail to respond to antiviral treatment
This spending item is part of a $903,136 allocation. See details
National Institutes of Health 8/17/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $660,770 Trans-NIH Recovery Act Research Support This application fits the broad Challenge Area (01): Behavior, Behavior Change, and Prevention (01); and specific Challenge Topic 01-CA-103: The role of health behaviors in cancer prevention. Skin cancer incidence is rising more rapidly than any other can National Institutes of Health 9/29/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $643,842 Trans-NIH Recovery Act Research Support The continuing development of efficient high-performance liquid chromatography (HPLC) protocols is critical for all areas of biomedical science and biotechnology. The major areas under investigation in our laboratory are: (1) development of novel and impr National Institutes of Health 8/03/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $616,360 Trans-NIH Recovery Act Research Support The function of millions of proteins remains unknown, and automated protein function prediction systems have a poor record of performance. We will test hypotheses about protein functional sites by validating high-throughput predictions derived from comput
This spending item is part of a $1,432,837 allocation. See details
National Institutes of Health 5/14/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $616,130 Trans-NIH Recovery Act Research Support Generalized vitiligo is the most common pigmentation disorder, autoimmune death of melanocytes resulting in white patches of skin and hair, and patients are at high risk of other autoimmune diseases such as thyroid disease, adult type 1 diabetes, rheumato National Institutes of Health 9/25/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $595,191 Trans-NIH Recovery Act Research Support One of medicine's greatest challenges today is the efficient, seamless translation of biomedical research discoveries into clinical applications. New methodologies, technologies and integrated information systems offer unprecedented promise for discovery
This spending item is part of a $863,573 allocation. See details
National Institutes of Health 9/26/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $573,629 Trans-NIH Recovery Act Research Support The potential role of extracellular proteases, namely the plasminogen activator/ plasminogen (PA/plgn) system in synaptic remodeling in the injured spinal cord of rodents will be the focus of these studies. The PA/plgn system has been suggested to play a National Institutes of Health 7/15/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $562,752 Trans-NIH Recovery Act Research Support During the past 25 years, studies in epithelial cancers have defined genetic changes in the tumor cells themselves. However, it is clear that cancer progression and metastasis requires complex interactions between tumor cells and the surrounding stromal. National Institutes of Health 5/15/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $557,523 Trans-NIH Recovery Act Research Support Despite decades of research, the immunological correlates of protection against HIV-1 infection in humans or SIV infection in nonhuman primates remain poorly understood. In contrast, studies on Friend retrovirus (FV)infection in mice highlighted the impor
This spending item is part of a $657,523 allocation. See details
National Institutes of Health 9/21/2009
LIMON DOCTORS COMMITTEE $546,730 ARRA Health Center Integrated Services Development Initiative[g1] ARRA-CIP Strasburg Expansion Project. Building construction-expansion for a total of 2,900 sq ft. Health Resources and Services Administration 6/25/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $531,818 Trans-NIH Recovery Act Research Support This P30 application seeks to provide resources to recruit Dr. Eric Schmidt to lead the Molecular Physiology and Imaging Core (MPIC) in the Division of Pulmonary Sciences and Critical Care Medicine. The Division is based at the University of CO Denver and
This spending item is part of a $1,041,830 allocation. See details
National Institutes of Health 9/21/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $523,289 Trans-NIH Recovery Act Research Support The overall goal of this proposal is to understand the contribution of metabolic, behavioral and diabetes-specific risk factors to the development of cardiovascular sub-clinical abnormalities in adolescents and young adults with T1D, as compared to non-di
This spending item is part of a $1,522,341 allocation. See details
National Institutes of Health 9/21/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $512,180 Trans-NIH Recovery Act Research Support This application addresses the broad Challenge Area (15) Translational Science, 15-CA-103: Thyroid Cancer Cell Line Project which is in direct response to our recent discovery showing that 17 out of 40 'thyroid' cancer cell lines are either redundant or m
This spending item is part of a $999,914 allocation. See details
National Institutes of Health 9/29/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $500,000 Trans-NIH Recovery Act Research Support Spinning Disk Confocal Microscope system. Eleven Major Users and 4 Minor Users, each with ongoing NIH grant support and extensive technical experience and expertise in fluorescence microscopy, request funds to purchase a Marianas SDC spinning disk microsc National Institutes of Health 4/29/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $500,000 Trans-NIH Recovery Act Research Support The aims of this Translational Conte Center are (1) to enhance the basic molecular and neurobiological characterization of the role of the alpha7 nicotinic acetylcholine receptor in the brain and its dysfunction in schizophrenia; (2) to use this biology t National Institutes of Health 5/19/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $496,938 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (03) Biomarker Discovery and Validation, and the specific Challenge Topic that this application addresses is: 03-DK-101 Discovery of biomarkers for disease risk, progression or response to therapy in disease National Institutes of Health 4/01/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $487,221 Trans-NIH Recovery Act Research Support This application addresses the Challenge Area 06 of 'Enabling Technologies and Prevention' and the specific Challenge Topic 06-HL-104 of 'enabling technologies involving the development of nanotools for pulmonary medicine, particularly aimed at safer and
This spending item is part of a $999,999 allocation. See details
National Institutes of Health 9/18/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $467,942 Trans-NIH Recovery Act Research Support We request funds to purchase a supercontinuum STED microscope. The STED (STimulated Emission Depletion) microscope, invented by Stefan Hell, is the first light microscope to break the Abbi diffraction limit. Abbi's barrier, a fundamental law of physics, s National Institutes of Health 7/01/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $449,693 Trans-NIH Recovery Act Research Support This application is an extension of our funded 2000 Trauma Center application and a resubmission of our competing renewal thaw was awarded bridge funding for 2004-2005. Our global hypothesis is that twoway exchanges between Human Core (housing clinical da National Institutes of Health 6/22/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $445,637 Trans-NIH Recovery Act Research Support The Computational Bioscience Program (CBP) of the University of Colorado School of Medicine is an independent Ph.D.-granting and postdoctoral training program. We have an innovative and highly productive approach to training pre- and post-doctoral fellows National Institutes of Health 7/23/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $417,474 Trans-NIH Recovery Act Research Support One of medicine's greatest challenges today is the efficient, seamless translation of biomedical research discoveries into clinical applications. New methodologies, technologies and integrated information systems offer unprecedented promise for discovery
This spending item is part of a $588,815 allocation. See details
National Institutes of Health 9/28/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $417,226 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work - The Tri-County Health Department, the largest local health department in Colorado which serves more than a million residents of Adams, Arapahoe and Douglas Counties, will partner with schoo... Show more
This spending item is part of a $10,511,509 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $410,907 Trans-NIH Recovery Act Research Support Chronic alcohol abuse has a variety of pathological consequences including damage to liver, brain and other organs. Some of these pathological effects can be attributed to ethanol metabolism. Ethanol is metabolized to acetaldehyde by the alcohol dehydroge National Institutes of Health 5/22/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $403,691 Trans-NIH Recovery Act Research Support The E4508 randomized phase II clinical trial will evaluate the combination of chemotherapy with EGFR inhibition, IGF-1R inhibition or both. Although the clinical study accrual rate is estimated at 12 months, there will be an interim toxicity analysis requ
This spending item is part of a $797,350 allocation. See details
National Institutes of Health 7/16/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $388,900 Trans-NIH Recovery Act Research Support One of medicine's greatest challenges today is the efficient, seamless translation of biomedical research discoveries into clinical applications. New methodologies, technologies and integrated information systems offer unprecedented promise for discovery
This spending item is part of a $557,157 allocation. See details
National Institutes of Health 9/24/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $383,958 Trans-NIH Recovery Act Research Support Natural Killer T (iNKT) cells represent a lymphocyte population that has evolved to recognize glycolipid antigens presented by CD1d. Upon recognition of glycolipids, iNKT cells respond within hours, reminiscent of innate rather than adaptive functions. Th National Institutes of Health 5/21/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $379,317 Trans-NIH Recovery Act Research Support American Indians and Alaska Natives (AI/ANs) suffer from marked health disparities when compared to other Americans; mortality rates associated with substance use, accidents, diabetes, homicide, and suicide are unacceptably high. While making health servi
This spending item is part of a $999,440 allocation. See details
National Institutes of Health 6/21/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $378,964 Trans-NIH Recovery Act Research Support Functional changes in the 2-adrenergic system play an important role in the pathophysiology of heart failure (HF) in adults. Experimental data has extensively defined many of the components involved in the 2-adrenergic receptor (2-AR) response in HF resul
This spending item is part of a $412,556 allocation. See details
National Institutes of Health 8/14/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $377,982 The purpose of this procurement is to obtain contract development services that will develop and test computational approaches to on or more cognitive problems as commonly encountered by clinical researcher, biologis, or patient. Artificial neural nets, National Institutes of Health 9/21/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $377,200 Trans-NIH Recovery Act Research Support Gonadotropin releasing hormone (GnRH) neurons originate in or near the olfactory placode and migrate into the forebrain during embryogenesis. Disruption of GnRH neuronal migration or production results in abnormal reproductive function in humans. Axl is a National Institutes of Health 8/11/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $365,042 Trans-NIH Recovery Act Research Support The University of Colorado Cancer Center (UCCC) is the only NCI-designated comprehensive Cancer Center in the Rocky Mountain region - an area with a population of approximately eight million people. The goals are to reduce the cancer burden by: 1) conduct National Institutes of Health 9/29/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $349,606 Trans-NIH Recovery Act Research Support Project Summary Abstract Prostate cancer (PCA) is the most frequently diagnosed invasive malignancy in the United States men and is the second leading cause of cancer-related deaths after lung (1). Chemoprevention of PCA has been suggested as a novel and National Institutes of Health 9/29/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $341,095 Trans-NIH Recovery Act Research Support Poliovirus and related human enteroviruses cause a diverse spectrum of human diseases including acuteflaccid paralysis (paralytic poliomyelitis), aseptic meningitis, myocarditis, conjunctivitis and fatal systemicinfections of neonates. Poliovirus (PV), th National Institutes of Health 6/04/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $333,282 Trans-NIH Recovery Act Research Support Pathological vascular remodeling is a key component and frequently life-threatening consequence, of vascular diseases in both the systemic and pulmonary circulation. In a neonatal model of hypoxic pulmonary hypertension, we have demonstrated that hypoxia- National Institutes of Health 7/16/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $320,525 Trans-NIH Recovery Act Research Support Extracellular nucleotides liberated at inflammatory tissue sites are metabolized to adenosine by surface expressed ecto-nucleotidases (CD73 and CD39). Ongoing studies indicate that adenosine liberated by this process is available to activate surface adeno National Institutes of Health 7/16/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $318,686 Trans-NIH Recovery Act Research Support The overall goal of this proposal is to reconstitute the signaling process in space and time in cancer cells and to integrate the new experimental data into a computational model of the dynamics of the EGFR-MAPK pathway. Firstly, the components of the MAP National Institutes of Health 5/07/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $318,686 Trans-NIH Recovery Act Research Support The overall goal of this proposal is to reconstitute the signaling process in space and time in cancer cells and to integrate the new experimental data into a computational model of the dynamics of the EGFR-MAPK pathway. Firstly, the components of the MAP National Institutes of Health 5/07/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $314,823 Trans-NIH Recovery Act Research Support Allergic reactions to peanuts occur because susceptible individuals have an aberrant response to peanuts by producing a plasma protein, IgE, that binds to the high affinity receptor for IgE, FceRI, on mast cells and basophils. This IgE can be cross-linked National Institutes of Health 9/21/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $301,204 Trans-NIH Recovery Act Research Support Schizophrenia is a chronic and debilitating mental illness with a prevalence of approximately 1%. A number of candidate genes are presently being investigated, although none has been definitively connected to the etiology of the disorder. Genetic linkag National Institutes of Health 7/16/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $300,816 Trans-NIH Recovery Act Research Support The HALT-PKD study is the first prospective clinical interventional study for autosomal dominant polycystic disease (ADPKD). The goal of the HALT PKD study is to slow or prevent the progression of the kidney and heart disease in patients with early (Study National Institutes of Health 9/21/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $300,027 Trans-NIH Recovery Act Research Support One of medicine's greatest challenges today is the efficient, seamless translation of biomedical research discoveries into clinical applications. New methodologies, technologies and integrated information systems offer unprecedented promise for discovery
This spending item is part of a $399,388 allocation. See details
National Institutes of Health 9/25/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $295,212 ARRA ? Equipment to Enhance Training for Health Professionals To purchase equipment that will be used to enhance training for Health Professionals Health Resources and Services Administration 9/04/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $290,515 Trans-NIH Recovery Act Research Support One of medicine's greatest challenges today is the efficient, seamless translation of biomedical research discoveries into clinical applications. New methodologies, technologies and integrated information systems offer unprecedented promise for discovery
This spending item is part of a $499,942 allocation. See details
National Institutes of Health 9/29/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $275,946 Trans-NIH Recovery Act Research Support The parent grant for this ARRA supplemental funding is National Cancer Institute R01 grant 1R01CA131386-01A1. The major focus of the parent R01 grant was to develop and evaluate the effects of Spanish and English language versions of a personally tailored
This spending item is part of a $528,993 allocation. See details
National Institutes of Health 8/31/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $272,986 Trans-NIH Recovery Act Research Support Aim 1 will use PA segments isolated from chronically hypoxic calves and mice and in vitro pulmonary artery vascular cells isolated from the neonatal calf to evaluate production of reactive oxygen species and expression and activity of EC-SOD. Aim 2 will u National Institutes of Health 7/16/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $268,763 Trans-NIH Recovery Act Research Support The packaging of the eukaryotic genome together with histone proteins into chromatin has profound implications for all processes that occur on the DMA template, including replication, transcription and repair. Chromatin assembly and disassembly are essent National Institutes of Health 7/16/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $260,220 ARRA ? Equipment to Enhance Training for Health Professionals ARRA - Equipment to enhance Training for Health Professionls. To purchase equipment that will be used to enhance training for Health Professionals. PROJECT SUMMARY CERT?s (Centers of Excellence in Rural Training) is a community-based pr... Show more Health Resources and Services Administration 9/02/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $252,914 Trans-NIH Recovery Act Research Support This project is an administrative supplement for the International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Group, specifically for additional work under protocols P1086 and P1088.
This spending item is part of a $259,237 allocation. See details
National Institutes of Health 5/24/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $252,780 Trans-NIH Recovery Act Research Support Numerous human disorders arise from microdeletions and microduplications of relatively large genomic regions. These rearrangements can result in copy number alterations (CNAs) of one or more genes. Conditions arising from microdeletions and microduplicati National Institutes of Health 3/08/2010
ADAMS, COUNTY OF $250,000 ARRA Strengthening Communities Fund The goal of the program is to build our capacity to partner with community-based and faith-based non-profits and to provide training and technical assistance to help nonprofit faith-based and community organizations better serve those in need and to incre Administration for Children and Families 9/19/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $242,638 The Systolic Blood pressure Intervention Trial, (SPRINT) contractor will conduct a multicenter, randomized clinical trial to determine whether treating systolic blood pressure to a lower goal than currently recommended, will reduce cardiovascular disease.
This spending item is part of a $2,491,798 allocation. See details
National Institutes of Health 9/24/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $236,690 Trans-NIH Recovery Act Research Support The long-term objective of this proposal is to understand the cellular processes that regulate high-fidelity eukaryotic DNA replication. Low fidelity replication and error-prone post-replication DNA repair can result in chromosomal aneuploidy and mutation National Institutes of Health 8/31/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $236,435 Trans-NIH Recovery Act Research Support It is the recommendation of the American Academy of Pediatrics that all children be breast-fed for at least the first six months of life [2], Despite this recommendation, the functional development of the mammary gland and the result of that development, National Institutes of Health 9/01/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $236,132 Trans-NIH Recovery Act Research Support This application is for a 5 year renewal of the Colorado Clinical Nutrition Research Unit (CNRU). The Colorado CNRU was originally funded in January, 1995 to serve 41 investigators. Now, in our eleventh year of operation, we serve 67 investigators.The bro
This spending item is part of a $295,456 allocation. See details
National Institutes of Health 7/20/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $235,573 Trans-NIH Recovery Act Research Support Chronic beryllium disease (CBD) is a granulomatous lung disorder caused by beryllium exposure in the workplace and is characterized by the accumulation of beryllium-specific CD4+ T cells in the lung. Due to its unique chemical and physical properties, ber National Institutes of Health 7/16/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $235,000 Technical support and administrative/management services: Task Order 6, Antiviral and Immune Plasma Infrastructure Development
This spending item is part of a $12,962,657 allocation. See details
National Institutes of Health 9/28/2009
ADAMS, COUNTY OF $231,750 ARRA - Head Start Adams County Head Start 2009 ARRA COLA and Quality Improvement Funding. Adams County Head Start serves primarily low income children ages 3 to 5 providing comprehensive services addressing the educational and health needs of children, and offeres family s Administration for Children and Families 6/30/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $229,875 Trans-NIH Recovery Act Research Support During chronic human immunodeficiency virus (HIV) infection, HIV-specific T cells fail to control viral replication, in part because they lose the ability to proliferate, produce cytokines, and lyse infected target cells. Functional restoration of HIV-spe National Institutes of Health 8/14/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $229,220 Trans-NIH Recovery Act Research Support The hypothesis to be examined in this project is that biliary atresia is associated with an increased frequency of certain HLA genotypes and novel shared HLA epitopes, suggesting a role for autoimmunity in the pathogenesis of this disease. This is an anci National Institutes of Health 9/30/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $223,313 Trans-NIH Recovery Act Research Support This competing renewal investigates the involvement of the protein tyrosine phosphatase family of diabetic autoantigens, phogrin (IA-2 beta) and ICA-512 (IA-2) and their invertebrate homologs as targets of T-cells and antibodies in type 1diabetes in the N National Institutes of Health 4/12/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $214,512 Trans-NIH Recovery Act Research Support Diabetes mellitus (DM) is increasingly prevalent among youth, forecasting early complications. Type 1 (T1D) and Type 2 diabetes (T2D) cause premature cardiovascular disease (CVD), shortening lifespan despite advances in glycemic control and CV risk factor National Institutes of Health 7/30/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $212,831 Trans-NIH Recovery Act Research Support The proposed Rocky Mountain Taste and Smell Center (RMTSC) will encompass twelve principal investigators including scientists with a substantial record of accomplishment in the field of chemical senses as well as investigators with expertise in other area National Institutes of Health 7/17/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $201,890 Trans-NIH Recovery Act Research Support Understanding how apoptosis is regulated in salivary gland cells is critical for the development of therapeutics to protect salivary glands from irradiation induced damage and for the treatment of Sjogren's syndrome, salivary tumors and other diseases to National Institutes of Health 9/22/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $200,002 Trans-NIH Recovery Act Research Support Significant morbidity and mortality of diabetes results from its complications of renal impairment, accelerated cardiovascular disease, and loss of vision. Abnormal vascular remodeling are integral components of diabetic macro-vascular and micro-vascular National Institutes of Health 9/30/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $197,612 Trans-NIH Recovery Act Research Support We have demonstrated that the in a rat model. The overall hypothesis presented in this grant provides an integrated pathophysiological schema whereby the IGF-l/Akt/mTOR/p70S6 kinase signaling pathway can lead to apoptosis and proliferation, cyst formation National Institutes of Health 9/30/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $194,788 Trans-NIH Recovery Act Research Support Current nutritional strategies for very preterm infants in this country are resulting in postnatal growth failure from which the neonate does not recover by the time of hospital discharge. Undernutrition, particularly insufficient protein intake during cr National Institutes of Health 9/30/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $187,982 Recovery Act Comparative Effectiveness Research - AHRQ Project summary/abstract Clinicians who care for persons with complex chronic medical conditions face both competing demands and a lack of evidence regarding best processes of care for this heterogeneous population. Those clinicians facing decis... Show more
This spending item is part of a $462,430 allocation. See details
Agency for Healthcare Research and Quality 9/28/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $187,665 Trans-NIH Recovery Act Research Support Despite significant efforts, our understanding of clinically relevant mechanisms underlying human pituitary tumorigenesis remains ashamedly meager. My lab has focused on defining the precise molecular mechanisms by which ubiquitous components of growth fa National Institutes of Health 8/04/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $186,929 ARRA - Maternal and Child Health (MCH) Pediatric Research Network Program Overall Purpose: Minor blunt head trauma in children is common. Although important traumatic brain injuries are infrequent, clinicians obtain cranial computed tomography (CT) in up to 50% of children with minor blunt head trau... Show more
This spending item is part of a $3,498,012 allocation. See details
Health Resources and Services Administration 7/28/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $186,131 Trans-NIH Recovery Act Research Support The University of Colorado Reproductive Medicine Unit (UC-RMU) is uniquely positioned to be an active and valuable participant in the Cooperative Multi-Center Reproductive Medicine Network of the NICHD. This proposal is jointly submitted by the Sections o National Institutes of Health 9/30/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $181,924 Trans-NIH Recovery Act Research Support The nasal cavity in mammals houses distinct chemosensory epithelia including the main olfactory epithelium, the vomeronasal epithelium and the trigeminally innervated respiratory epithelium (so-called 'non- sensory' epithelium) (Finger et al., 2000). Each National Institutes of Health 8/14/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $175,085 Trans-NIH Recovery Act Research Support Gene therapy has long been touted to hold the promise of cure for a variety of congenital diseases. However, gene therapy trials are still small in number and scale due to several problems that have prevented wider application of current technology. Ineff National Institutes of Health 8/01/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $174,083 Trans-NIH Recovery Act Research Support Multiple studies have documented significantly lower plasma HIV-1 RNA concentrations (VL) in women compared to men at CD4+ T cell counts greater than 300 cells/mm3. Mechanisms underlying sex differences in VL are unknown. Because most HIV-1 replication oc National Institutes of Health 7/29/2010
ADAMS 12 FIVE STAR SCHOOLS $166,257 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work - The Tri-County Health Department, the largest local health department in Colorado which serves more than a million residents of Adams, Arapahoe and Douglas Counties, will partner with schoo... Show more
This spending item is part of a $10,511,509 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
BRIGHTON SCHOOL DISTRICT 27J $164,875 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work - The Tri-County Health Department, the largest local health department in Colorado which serves more than a million residents of Adams, Arapahoe and Douglas Counties, will partner with schoo... Show more
This spending item is part of a $10,511,509 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
ADAMS COUNTY SCHOOL DISTRICT 14 $164,745 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work - The Tri-County Health Department, the largest local health department in Colorado which serves more than a million residents of Adams, Arapahoe and Douglas Counties, will partner with schoo... Show more
This spending item is part of a $10,511,509 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
ADAMS COUNTY SCHOOL DISTRICT #1 $163,170 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work - The Tri-County Health Department, the largest local health department in Colorado which serves more than a million residents of Adams, Arapahoe and Douglas Counties, will partner with schoo... Show more
This spending item is part of a $10,511,509 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $161,200 We have been awarded a contract to provide tumor types to the NCI for The Cancer Genome Atlas (TCGA) project. Specifically to establish a Tissue Source Site (TSS) Network capable of delivering clinically annotated biospecimens through either or both retr
This spending item is part of a $1,627,009 allocation. See details
National Institutes of Health 9/27/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $160,373 Trans-NIH Recovery Act Research Support The goal of this proposal is to understand synaptic transmission at the vestibular type I hair cell/calyx synapse. Three classes of morphological afferents have been described in the amniote crista and utricle. Calyx units contact type I hair cells (HCI) National Institutes of Health 7/17/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $154,586 Trans-NIH Recovery Act Research Support The goals of this application are to address the development of CD40+ T cells, the role that CD40 plays in T cell receptor (TCR) revision and how induced TCR revision impacts autoimmunity. CD40 has a direct role in autoimmune diseases including type 1 dia National Institutes of Health 1/20/2010
CHILDREN'S HOSPITAL ASSOCIATION, THE $153,974 Trans-NIH Recovery Act Research Support In this application, the Principal and Co-investigators propose the development of a coordinated and integrated 'Rare Liver Disease Network' (RLDN) as a Rare Diseases Clinical Research Center in response to NIH RFA RR 03-008. The RLDN will focus on invest National Institutes of Health 2/17/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $153,680 Trans-NIH Recovery Act Research Support Gammaherpesviruses cause lifelong infection and are associated with various diseases, particularly in immune deficient hosts. The human gammaherpesviruses, Epstein Barr virus (EBV) and Kaposi's sarcoma associated virus, are associated with a number of mal National Institutes of Health 5/07/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $153,334 Trans-NIH Recovery Act Research Support By early childhood, children who will later develop a primary psychotic disorder are already demonstrating many of the deficits that are closely associated with the disease in the adult. For example, even though diagnostic symptomotology may be a decade o National Institutes of Health 5/27/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $153,334 Trans-NIH Recovery Act Research Support Bacterial infection of lung airways underlies some of the main complications of COPD, which impact significantly in disease progression and outcome. Acute exacerbations (AE) represent one of the major contributing factors of morbidity, clinical deteriorat National Institutes of Health 5/08/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $153,000 Trans-NIH Recovery Act Research Support The primary goal of this application is to identify genes and other genomic features that underlie the action of alcohol. While we have made considerable progress toward this objective through the use mouse quantitative trait loci (QTL) mapping, gene exp National Institutes of Health 8/09/2010
Town of Bennett $151,000 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work - The Tri-County Health Department, the largest local health department in Colorado which serves more than a million residents of Adams, Arapahoe and Douglas Counties, will partner with schoo... Show more
This spending item is part of a $10,511,509 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $150,983 Trans-NIH Recovery Act Research Support The control of gene expression at the level of transcription by RNA polymerase II is central to the life of the healthy cell and is frequently corrupted in disease. During each stage of the transcription cycle, initiation, elongation and termination, the National Institutes of Health 12/11/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $150,293 Trans-NIH Recovery Act Research Support Look AHEAD is randomized clinical trial examining the long-term health effects of an intensive weight loss intervention in approximately 5,145 overweight volunteers with type 2 diabetes. Participants are randomized to an intensive lifestyle intervention d National Institutes of Health 9/28/2009
THORNTON, CITY OF $150,000 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work - The Tri-County Health Department, the largest local health department in Colorado which serves more than a million residents of Adams, Arapahoe and Douglas Counties, will partner with schoo... Show more
This spending item is part of a $10,511,509 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $149,896 Trans-NIH Recovery Act Research Support Thyroid cancer is the most common endocrine malignancy with an annual incidence of 21,000 in the U.S. 5- 10% of patients have advanced thyroid cancer that is unresponsive to standard therapy, and 1,500 patients die each year from this disease. There are C National Institutes of Health 8/31/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $148,877 Trans-NIH Recovery Act Research Support The challenge addressed in this proposal is to better understand the remarkable increase in the prevalence of atopic diseases (atopic dermatitis (AD), food allergy, asthma, and atopic rhinitis) over the last 4-5 decades and the extent to which epigenetic
This spending item is part of a $930,848 allocation. See details
National Institutes of Health 9/29/2009
CHILDREN'S HOSPITAL ASSOCIATION, THE $143,500 Trans-NIH Recovery Act Research Support Cholestatic liver diseases are among the most important liver disorders that occur in infants and children, leading to devastating morbidity and accounting for over 70% of liver transplants performed during childhood, posing a major public health burden. National Institutes of Health 3/11/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $141,326 Trans-NIH Recovery Act Research Support On behalf of the Reproductive Medicine Network (RMN), we, as the Data Coordination Center, submit this request in response to NIH announcement NOT-OD-09-056 for a Recovery Act administrative supplement. We will use the supplement to field a comparative ef
This spending item is part of a $7,565,277 allocation. See details
National Institutes of Health 9/30/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $139,824 Trans-NIH Recovery Act Research Support Rheumatoid arthritis (RA) is the most common type of inflammatory arthritis; while there are now many effective medications to treat it, these drugs vary greatly in cost (up to $15,000/year) and side effects and there is no way to predict which drug is be
This spending item is part of a $3,344,252 allocation. See details
National Institutes of Health 9/29/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $138,156 Trans-NIH Recovery Act Research Support A major challenge in vaccinology is that the efficacy of a vaccine can only be ascertained retrospectively, upon infection. The identification of molecular signatures induced rapidly after vaccination, which correlate with and predict, the later developme
This spending item is part of a $3,213,142 allocation. See details
National Institutes of Health 7/12/2010
Bennett School District 29 J $137,807 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work - The Tri-County Health Department, the largest local health department in Colorado which serves more than a million residents of Adams, Arapahoe and Douglas Counties, will partner with schoo... Show more
This spending item is part of a $10,511,509 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
Adams Arapahoe 28j $137,586 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work - The Tri-County Health Department, the largest local health department in Colorado which serves more than a million residents of Adams, Arapahoe and Douglas Counties, will partner with schoo... Show more
This spending item is part of a $10,511,509 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
ADAMS COUNTY SCHOOL DISTRICT #50 $133,762 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work - The Tri-County Health Department, the largest local health department in Colorado which serves more than a million residents of Adams, Arapahoe and Douglas Counties, will partner with schoo... Show more
This spending item is part of a $10,511,509 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $133,760 Trans-NIH Recovery Act Research Support The taste periphery comprises a distributed array of taste buds innervated by distinct cranial nerves. In recent years, theories of the embryonic development of this system have undergone radical revision. Previously, taste buds were thought to be induced National Institutes of Health 7/17/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $122,434 Trans-NIH Recovery Act Research Support A major challenge in vaccinology is that the efficacy of a vaccine can only be ascertained retrospectively, upon infection. The identification of molecular signatures induced rapidly after vaccination, which correlate with and predict, the later developme
This spending item is part of a $3,213,142 allocation. See details
National Institutes of Health 7/12/2010
COMMERCE CITY, CITY OF $120,000 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work - The Tri-County Health Department, the largest local health department in Colorado which serves more than a million residents of Adams, Arapahoe and Douglas Counties, will partner with schoo... Show more
This spending item is part of a $10,511,509 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $110,811 Trans-NIH Recovery Act Research Support The control of mRNA/protein complexes (mRNPs) is critical to animal development and cell function. Little is known about how specific mRNPs are regulated, and how this control is organized in the cytoplasm of living cells. This project plans to use C. ele National Institutes of Health 1/08/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $108,622 Trans-NIH Recovery Act Research Support Pre-mRNA splicing is essential for gene expression in all eukaryotes and errors in splicing cause genetic disorders and many other diseases. Mutations in splicing factor Prp8, for example, cause a severe form of human genetic disorder Retinitis Pigmentosa National Institutes of Health 9/30/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $103,093 Trans-NIH Recovery Act Research Support Mucosal organs such as the intestine and lung are highly vascular organs with extensive metabolic demands. Epithelial cells which line the intestine function to orchestrate a multitude of mucosal responses, and given their anatomic location, are primary t National Institutes of Health 1/25/2010
CHILDREN'S HOSPITAL ASSOCIATION, THE $103,000 Trans-NIH Recovery Act Research Support Eosinophilic esophagitis (EE) is an emerging worldwide disease that mimics gastroesophageal reflux disease (GERD) and can lead to esophageal narrowing and stricture (1-4). EE is differentiated from GERD by the magnitude of mucosal eosinophilia and epithe
This spending item is part of a $930,342 allocation. See details
National Institutes of Health 9/18/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $100,000 Trans-NIH Recovery Act Research Support The long-term goal of this proposal is to define signaling pathways that control oncogenic transformation and epithelial to mesenchymal transition (EMT) of lung cancer cells. The secreted Wnt proteins, which signal through the Frizzled (Fz) family of seve National Institutes of Health 9/22/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $99,944 Trans-NIH Recovery Act Research Support The incidence of Down syndrome (DS) is one in 700 live births, the life expectancy is now >50 years, and the average IQ is approximately 50. Therefore, DS is a significant social and medical issue. Many phenotypic features of DS, including cognitive defic National Institutes of Health 7/07/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $99,901 Trans-NIH Recovery Act Research Support Urolithiasis is a multi-factorial disease and it is unlikely that a single factor will be responsible for the entire spectrum of this disorder. Nonetheless, oxalate and calcium-oxalate crystal (COM-crystal) interactions with renal epithelial cells, and th National Institutes of Health 11/20/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $99,841 Trans-NIH Recovery Act Research Support Project Summary. Biliary atresia (BA) is a progressive, inflammatory, sclerosing extrahepatic and intrahepatic cholangiopathy which presents in infancy and leads to bile duct obstruction and biliary cirrhosis. Intrahepatic biliary inflammation and scleros National Institutes of Health 2/16/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $99,008 Trans-NIH Recovery Act Research Support The overall hypothesis presented in this grant provides an integrated pathophysiological schema whereby caspase-1 and caspase-1-related cytokines like IL-18 and IL-1a lead to increased macrophage and NK cell infiltration in the kidney and resultant ischem National Institutes of Health 12/18/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $94,325 Trans-NIH Recovery Act Research Support The funds will be used to develop, open and analyze three H1N1 studies in HIV-infected populations. The first study will determine the safety and immunogenicity of an H1N1 vaccine in HIV-infected pregnant women. The second study will determine safety an
This spending item is part of a $1,701,287 allocation. See details
National Institutes of Health 11/25/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $92,330 Trans-NIH Recovery Act Research Support Background: In a) OVE26 mice with type 1 diabetes, b) C57BI/6 mice with diet induced obesity and insulin resistance, and c) db/db mice with type 2 diabetes mellitus, we have found increased renal expression of the transcriptional factors, i) the sterol re National Institutes of Health 12/08/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $92,289 Trans-NIH Recovery Act Research Support Traumatic brain injury (TBI) is a significant public health problem, with 1.5-2.0 million Americans injured each year. Cognitive deficits, particularly in the domains of memory and attention are frequently the source of lingering disability after TBI and
This spending item is part of a $271,198 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY COLORADO HOSPITAL AUTHORITY $91,597 Trans-NIH Recovery Act Research Support One of medicine's greatest challenges today is the efficient, seamless translation of biomedical research discoveries into clinical applications. New methodologies, technologies and integrated information systems offer unprecedented promise for discovery
This spending item is part of a $863,573 allocation. See details
National Institutes of Health 9/26/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $87,156 Trans-NIH Recovery Act Research Support The overarching goal of the Integrative Neuroscience Initiative on Alcoholism (INIA)-West Consortium is to identify the molecular, cellular, and behavioral neuroadaptations that occur in the brain reward circuits associated with the extended amygdala and National Institutes of Health 9/25/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $85,925 Trans-NIH Recovery Act Research Support The proposed project is to obtain equipment that utilizes the most modern technological advances in order to update our laser capture microdissection (LCM) equipment. LCM is a technology for isolating pure populations of cells from tissue sections. Cells National Institutes of Health 4/28/2009
THORNTON, CITY OF $85,600 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work - The Tri-County Health Department, the largest local health department in Colorado which serves more than a million residents of Adams, Arapahoe and Douglas Counties, will partner with schoo... Show more
This spending item is part of a $10,511,509 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $82,543 Trans-NIH Recovery Act Research Support Obesity, insulin resistance, diabetes mellitus, and aging are the leading causes of renal and cardiovascular disease. In addition to the important roles played by hypertension, abnormal carbohydrate metabolism, profibrotic growth factors, proinflammatory National Institutes of Health 8/04/2009
ADAMS, COUNTY OF $81,051 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work - The Tri-County Health Department, the largest local health department in Colorado which serves more than a million residents of Adams, Arapahoe and Douglas Counties, will partner with schoo... Show more
This spending item is part of a $10,511,509 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $80,986 Trans-NIH Recovery Act Research Support Renal failure is increasing at the rate of 6% with a cost of 16 billion dollars per year; thus developing new therapies for kidney disease is of paramount importance. In the previous renewal, we demonstrated that a loss of constitutive expression of vascu National Institutes of Health 9/07/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $80,113 Trans-NIH Recovery Act Research Support The function of millions of proteins remains unknown, and automated protein function prediction systems have a poor record of performance. We will test hypotheses about protein functional sites by validating high-throughput predictions derived from comput National Institutes of Health 9/23/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $79,284 Recovery Act Comparative Effectiveness Research - AHRQ Low back pain is one of the most important causes of functional limitation and disability, an Institute of Medicine priority condition, and it remains a particularly important problem for the elderly, an AHRQ priority population. While there are ... Show more
This spending item is part of a $9,887,064 allocation. See details
Agency for Healthcare Research and Quality 9/28/2010
RANGEVIEW LIBRARY DISTRICT $77,294 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work - The Tri-County Health Department, the largest local health department in Colorado which serves more than a million residents of Adams, Arapahoe and Douglas Counties, will partner with schoo... Show more
This spending item is part of a $10,511,509 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $76,708 Trans-NIH Recovery Act Research Support Viral-induced encephalitis remains a major cause of morbidity and mortality throughout the world. Effective therapies are available for only a few neurotropic viruses, and even when these infections are optimally treated, residual mortality and neurologic National Institutes of Health 9/24/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $75,746 Trans-NIH Recovery Act Research Support About 75% of birth defects involve the head, face, and oral tissues. Although orofacial clefts and other craniofacial malformations have clear environmental and genetic causes, insufficient information exists concerning the mechanisms of craniofacial deve National Institutes of Health 9/01/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $71,272 ARRA - Maternal and Child Health (MCH) Pediatric Research Network Program PROS has been funded by the Department of Health and Human Services (DHHS) and the Health Resources and Services Administration Maternal and Child Health Bureau (HRSA MCHB) for a three-year, $3.5 million project, in which a sam... Show more
This spending item is part of a $3,499,979 allocation. See details
Health Resources and Services Administration 8/27/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $70,443 Trans-NIH Recovery Act Research Support Hypoxic-ischemic (HI) encephalopathy is a common problem impacting thousands of Americans. Animal models have been created to allow for a greater understanding of the process and determine the efficacy of pharmaceutical agents. One of these is the hypoxia National Institutes of Health 9/25/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $69,706 Trans-NIH Recovery Act Research Support Communication in Late-stage Cancer: Exploring Hospice Decisions This application addresses broad Challenge Area (04): Clinical Research and specific Challenge Topic, 04-NR-103*: Methods to Enhance Palliative Care and End-of-Life Research. Estimates indica
This spending item is part of a $451,157 allocation. See details
National Institutes of Health 9/23/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $69,503 Trans-NIH Recovery Act Research Support This application addresses Recovery Act Limited Competition: Research and Research Infrastructure 'Grand Opportunities' (GO) (RC2): NIDCR guidelines, RFA-OD-09-004: Area of Scientific Priority 4) Detection of Oral Premalignant and Malignant Lesions. This
This spending item is part of a $770,000 allocation. See details
National Institutes of Health 9/28/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $68,686 Trans-NIH Recovery Act Research Support This application requests renewal of a NIDA-sponsored MERIT Award as a R01. The overall goal is to under- stand why individuals differ in cocaine-induced activation and, specifically, i) how the dopamine (DA) trans- porter (DAT) contributes to this differ National Institutes of Health 9/17/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $67,060 Trans-NIH Recovery Act Research Support Natural Killer T (iNKT) cells represent a lymphocyte population that has evolved to recognize glycolipid antigens presented by CD1d. Upon recognition of glycolipids, iNKT cells respond within hours, reminiscent of innate rather than adaptive functions. Th National Institutes of Health 9/20/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $66,194 Trans-NIH Recovery Act Research Support This proposal is for a Rare Cancer Genetics Registry (RCGR). The proposal is being submitted for Challenge Area: 07: Enhancing Clinical Trials and specific Challenge Topic: Rare Disease Genetic Patient Registry: 07-OD(ORDR)-102. We will develop a registry
This spending item is part of a $987,770 allocation. See details
National Institutes of Health 9/29/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $66,015 Trans-NIH Recovery Act Research Support There is a demonstrated community need for an annotated corpus consisting of the full texts of biomedical journal articles. There are many reasons to believe that the rate-limiting factor impeding progress in biomedical language processing today is the la National Institutes of Health 7/22/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $65,984 Trans-NIH Recovery Act Research Support Two aims are proposed. Aim 1. Test the hypothesis that centrifugal noradrenergic modulation of olfactory bulb function is necessary for discrimination of closely related odors. Aim 2. Test the hypothesis that noradrenaline modulates cellular properties a National Institutes of Health 7/17/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $64,158 Trans-NIH Recovery Act Research Support The long-term objective of our laboratory is to understand changes in gene expression and regulation that occur during insulin resistance and diabetes which permit excessive SMC activation. We recently reported that overexpression of the cAMP Response Ele National Institutes of Health 9/18/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $60,235 Trans-NIH Recovery Act Research Support Taste transduction begins when sapid stimuli interact with the apical membrane of receptor cells, causing an increase in intracellular Ca 2+. This ultimately results in release of transmitter and activation of gustatory afferent fibers. Several G protein- National Institutes of Health 7/17/2009
CHILDREN'S HOSPITAL ASSOCIATION, THE $60,136 Recovery Act Comparative Effectiveness Research - AHRQ EHRs have the potential to anchor a learning healthcare system where each clinical encounter is an opportunity to learn and to improve clinical outcomes. We propose to link EHRs to disease-specific registries in a distributed network of pediatric... Show more
This spending item is part of a $11,743,165 allocation. See details
Agency for Healthcare Research and Quality 9/28/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $54,000 Trans-NIH Recovery Act Research Support Because trials to compare digital and analog mammography rely on complex designs, cost large amounts of money and involve the health of many women, accurate power and sample size calculations are essential. In these trials, radiologists read many films us National Institutes of Health 9/15/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $54,000 Trans-NIH Recovery Act Research Support The intestine is a complex and dynamic organ that, under normal physiologic conditions, performs a number of functions in the organism, some of which, including nutrient absorption, are essential for survival. The intestine is subject to pathologic distur National Institutes of Health 1/19/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $53,495 Trans-NIH Recovery Act Research Support In order to generate the craniofacial skeleton, neural crest progenitors need to adopt one specific fate verses another. It is the long-term goal of my laboratory to determine the molecular mechanisms that regulate cell fate determination of neural crest National Institutes of Health 9/22/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $53,103 Trans-NIH Recovery Act Research Support The long term goal is to identify molecular mechanisms of cancer initiation and progression and hence to improve cancer prognosis and therapy. Smads are transcription factors initially identified as signaling molecules for the transforming growth factor National Institutes of Health 6/01/2009
Adams County Foundation Inc $52,994 ARRA Child Care and Development Block Grant The CCDF ARRA funds will be used to provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $24,312,305 allocation. See details
Administration for Children and Families 4/09/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $51,018 Trans-NIH Recovery Act Research Support The goals of this project are to understand the concurrent development of the acoustical cues to sound source location and the neural circuits that encode them. All cues for localization can be captured in measurements of head related directional transfer National Institutes of Health 8/14/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $50,000 Trans-NIH Recovery Act Research Support The focus of my career in patient-oriented research (POR) has been to study how interactions between HIV- 1 and key cells involved in innate and adaptive immunity influence control of HIV-1 replication and disease progression. The ultimate goal of these s National Institutes of Health 8/02/2010
Bennett School District 29 J $50,000 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work - The Tri-County Health Department, the largest local health department in Colorado which serves more than a million residents of Adams, Arapahoe and Douglas Counties, will partner with schoo... Show more
This spending item is part of a $10,511,509 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
ADAMS COUNTY SCHOOL DISTRICT 14 $50,000 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work - The Tri-County Health Department, the largest local health department in Colorado which serves more than a million residents of Adams, Arapahoe and Douglas Counties, will partner with schoo... Show more
This spending item is part of a $10,511,509 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $50,000 Trans-NIH Recovery Act Research Support The funds will be used to develop, open and analyze three H1N1 studies in HIV-infected populations. The first study will determine the safety and immunogenicity of an H1N1 vaccine in HIV-infected pregnant women. The second study will determine safety an
This spending item is part of a $1,701,287 allocation. See details
National Institutes of Health 11/25/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $50,000 Trans-NIH Recovery Act Research Support Severe acute respiratory syndrome (SARS), caused by a new human coronavirus (SARS-CoV), represents the 21st century's first pandemic caused by a previously unknown etiological agent. The 2002-03 SARS epidemic stimulated research on coronaviruses of humans National Institutes of Health 8/02/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $50,000 Trans-NIH Recovery Act Research Support The funds will be used to develop, open and analyze three H1N1 studies in HIV-infected populations. The first study will determine the safety and immunogenicity of an H1N1 vaccine in HIV-infected pregnant women. The second study will determine safety an
This spending item is part of a $1,701,287 allocation. See details
National Institutes of Health 11/25/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $50,000 Trans-NIH Recovery Act Research Support The University of Colorado Cancer Center (UCCC) is the only NCI-designated comprehensive Cancer Center in the Rocky Mountain region - an area with a population of approximately eight million people. The goals are to reduce the cancer burden by: 1) conduct National Institutes of Health 9/28/2009
Adams Arapahoe 28j $50,000 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work - The Tri-County Health Department, the largest local health department in Colorado which serves more than a million residents of Adams, Arapahoe and Douglas Counties, will partner with schoo... Show more
This spending item is part of a $10,511,509 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $50,000 Trans-NIH Recovery Act Research Support The focus of my career in patient-oriented research (POR) has been to study how interactions between HIV- 1 and key cells involved in innate and adaptive immunity influence control of HIV-1 replication and disease progression. The ultimate goal of these s National Institutes of Health 9/21/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $50,000 Trans-NIH Recovery Act Research Support Severe acute respiratory syndrome (SARS), caused by a new human coronavirus (SARS-CoV), represents the 21st century's first pandemic caused by a previously unknown etiological agent. The 2002-03 SARS epidemic stimulated research on coronaviruses of humans National Institutes of Health 9/11/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $49,999 Trans-NIH Recovery Act Research Support Neurotropic viruses are important causes of morbidity and mortality throughout the world. The lack of therapeutic options for these diseases is driven by the paucity of understanding of the mechanisms by which neurotropic viruses cause disease. We propose National Institutes of Health 9/11/2009
ADAMS COUNTY SCHOOL DISTRICT #1 $49,995 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work - The Tri-County Health Department, the largest local health department in Colorado which serves more than a million residents of Adams, Arapahoe and Douglas Counties, will partner with schoo... Show more
This spending item is part of a $10,511,509 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
ADAMS 12 FIVE STAR SCHOOLS $49,701 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work - The Tri-County Health Department, the largest local health department in Colorado which serves more than a million residents of Adams, Arapahoe and Douglas Counties, will partner with schoo... Show more
This spending item is part of a $10,511,509 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $49,582 Trans-NIH Recovery Act Research Support Neurotropic viruses are important causes of morbidity and mortality throughout the world. The lack of therapeutic options for these diseases is driven by the paucity of understanding of the mechanisms by which neurotropic viruses cause disease. We propose National Institutes of Health 8/02/2010
BRIGHTON SCHOOL DISTRICT 27J $49,550 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work - The Tri-County Health Department, the largest local health department in Colorado which serves more than a million residents of Adams, Arapahoe and Douglas Counties, will partner with schoo... Show more
This spending item is part of a $10,511,509 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $48,695 Trans-NIH Recovery Act Research Support The success of TNF blockade for the treatment of Crohn's disease (CD) has lead to the systematic study of other biological therapies. Unfortunately, the usefulness of these newer therapies (e.g. IL-10, IL-11 blockade) has been limited. Therefore, alternat National Institutes of Health 7/31/2009
ADAMS COUNTY SCHOOL DISTRICT #50 $48,416 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work - The Tri-County Health Department, the largest local health department in Colorado which serves more than a million residents of Adams, Arapahoe and Douglas Counties, will partner with schoo... Show more
This spending item is part of a $10,511,509 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $48,383 Trans-NIH Recovery Act Research Support The unifying goals of this P01 competing renewal are to further understand the immune, esposure, and genetic basis of chronic beryllium disease (CBD) and to discover and validate biological markers of disease prognosis and therapeutic response. National Institutes of Health 5/28/2010
Strasburg School Dist 31-J $48,283 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work - The Tri-County Health Department, the largest local health department in Colorado which serves more than a million residents of Adams, Arapahoe and Douglas Counties, will partner with schoo... Show more
This spending item is part of a $10,511,509 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $47,409 Trans-NIH Recovery Act Research Support Fatty acid ?-oxidation is the major energy-producing process in the liver, heart, and type 1 muscle fiber. It is carried out by a series of four reactions that successively cleave acetyl-CoA from fatty acyl-CoA. The rate of this process can be altered by
This spending item is part of a $720,582 allocation. See details
National Institutes of Health 8/14/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $42,070 To establish a coordinated process structured to meet previously-identified scientific needs for quantitative imaging biomarkers. The long-term objective is to establish processes and profiles that will lead to acceptance by the imaging community, clinica
This spending item is part of a $2,412,566 allocation. See details
National Institutes of Health 9/30/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $36,180 Trans-NIH Recovery Act Research Support The development of alcoholism related traits is believed to be caused by both genetic and environmental factors, in addition to their interactions. Genetic variations associated with alcoholism related traits can affect several different mechanisms, inclu National Institutes of Health 8/03/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $35,564 Trans-NIH Recovery Act Research Support With the discovery that mutations in fourteen different keratin genes can cause eight distinct epithelial fragility disorders, comes the realization that the keratin filament cytoskeleton is crucial to the structural integrity of epithelial tissues expose National Institutes of Health 6/10/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $35,077 Trans-NIH Recovery Act Research Support The broad mandate of this proposal is to use transgenic, molecular and biochemical approaches to determine the in\ vivo biological effects specific to the Pit-IB isoform with regards to Pit-1-dependent pituitary cell ontogeny and gene expression, and to d National Institutes of Health 12/03/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $35,025 Trans-NIH Recovery Act Research Support Treatment for schizophrenia involves both behavioral and rehabilitation interventions and pharmacotherapy. A number of studies have documented the effectiveness of various interventions and treatments for schizophrenia, but these studies fail to consider
This spending item is part of a $914,235 allocation. See details
National Institutes of Health 9/29/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $35,000 Trans-NIH Recovery Act Research Support In order to generate a functional nervous system, neural progenitors need to adopt one specific fate verses another. It is the long-term goal of my laboratory to determine the molecular mechanisms that regulate cell fate determination of neural crest and National Institutes of Health 7/07/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $33,880 Trans-NIH Recovery Act Research Support Little is known about the pathogenesis of pulmonary arterial hypertension (PAH) and the factors that contribute to its higher prevalence in HlV-infected patients. Chronic exposure to viral products in the lung as well as HlV-induced immune dysregulation m National Institutes of Health 5/30/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $33,482 Trans-NIH Recovery Act Research Support Our project addresses key issues in adult-to-adult living donor liver transplantation (LDLT). The Main Trial is an extension of the ongoing A2ALL Study - our program is an active participant and the leading enroller of patients to this trial. The current National Institutes of Health 9/30/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $33,037 Trans-NIH Recovery Act Research Support The funds will be used to develop, open and analyze three H1N1 studies in HIV-infected populations. The first study will determine the safety and immunogenicity of an H1N1 vaccine in HIV-infected pregnant women. The second study will determine safety an
This spending item is part of a $1,701,287 allocation. See details
National Institutes of Health 11/25/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $32,681 Trans-NIH Recovery Act Research Support About 75% of birth defects involve the head, face, and oral tissues. Although orofacial clefts and other craniofacial malformations have clear environmental and genetic causes, insufficient information exists concerning the mechanisms of craniofacial deve National Institutes of Health 3/10/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $32,460 Recovery Act Comparative Effectiveness Research - AHRQ The Scalable PArtnering Network for CER: Across Lifespan, Conditions, and Settings, or SPAN, will develop a distributed research network that is interoperable across a range of health care systems and sites, incorporating large and diverse patien... Show more
This spending item is part of a $8,272,272 allocation. See details
Agency for Healthcare Research and Quality 9/28/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $30,642 Trans-NIH Recovery Act Research Support Our project addresses key issues in adult-to-adult living donor liver transplantation (LDLT). The Main Trial is an extension of the ongoing A2ALL Study - our program is an active participant and the leading enroller of patients to this trial. The current National Institutes of Health 6/22/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $29,168 ARRA - Scholarships for Disadvantaged Students Financial Aid Health Resources and Services Administration 9/03/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $24,587 Trans-NIH Recovery Act Research Support Mammals that hibernate depress their metabolic, heart and respiratory rates, as well as their core body temperature (Tb) to enter a state called torpor. In hibernators such as ground squirrels, torpor is precisely controlled and fully reversible using onl National Institutes of Health 6/01/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $23,861 Trans-NIH Recovery Act Research Support Fatty acid ?-oxidation is the major energy-producing process in the liver, heart, and type 1 muscle fiber. It is carried out by a series of four reactions that successively cleave acetyl-CoA from fatty acyl-CoA. The rate of this process can be altered by
This spending item is part of a $720,582 allocation. See details
National Institutes of Health 8/14/2009
BRIGHTON SCHOOL DISTRICT 27J $23,739 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work - The Tri-County Health Department, the largest local health department in Colorado which serves more than a million residents of Adams, Arapahoe and Douglas Counties, will partner with schoo... Show more
This spending item is part of a $10,511,509 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $22,625 Poor outcomes are common for heart failure (HF) patients with 1-year readmission rates over 50% and 1-year mortality greater than 30% among Medicare Beneficiaries hospitalized with heart failure.} Heart failure is also the top diagnosis for hospitalizatio
This spending item is part of a $2,073,232 allocation. See details
Agency for Healthcare Research and Quality 7/13/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $19,256 Trans-NIH Recovery Act Research Support Pending National Institutes of Health 6/05/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $18,670 Trans-NIH Recovery Act Research Support The parent grant is a R01 that funds a randomized controlled trial of the Fostering Healthy Futures preventive intervention for preadolescent children placed in out-of-home care as a result of abuse or neglect. The intervention is designed to promote chi National Institutes of Health 6/16/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $18,417 The funds will be used for the following purposes in support of the Accelerating Clinical Trials of Novel Oncologic PathWays (ACTNOW) project: 1) acceleration of IRB approvals with additional regulatory personnel at each site; 2) additional patient naviga
This spending item is part of a $942,533 allocation. See details
National Institutes of Health 8/31/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $18,090 Trans-NIH Recovery Act Research Support We have shown that PGIS promoter variants lead to functional differences in mRNA expression. Because of the rich variety of promoter sequence variants and their close association with a variable number of tandem repeats, direct DNA sequencing has been th National Institutes of Health 9/14/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $13,470 Trans-NIH Recovery Act Research Support The funds will be used to develop, open and analyze three H1N1 studies in HIV-infected populations. The first study will determine the safety and immunogenicity of an H1N1 vaccine in HIV-infected pregnant women. The second study will determine safety an
This spending item is part of a $1,701,287 allocation. See details
National Institutes of Health 11/25/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $13,103 Trans-NIH Recovery Act Research Support ARRA Administrative Supplement: Providing Summer Research Experience for Students and Science Educators National Institutes of Health 6/23/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $13,075 Trans-NIH Recovery Act Research Support The funds will be used to develop, open and analyze three H1N1 studies in HIV-infected populations. The first study will determine the safety and immunogenicity of an H1N1 vaccine in HIV-infected pregnant women. The second study will determine safety an
This spending item is part of a $1,701,287 allocation. See details
National Institutes of Health 11/25/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $10,000 Trans-NIH Recovery Act Research Support This project will take advantage of the existing infrastructure of the PHACS Study which began protocol development in 2005 after successfully competing for funding by the NICHD. This is a multicenter, multidisciplinary and collaborative study. The PHACS
This spending item is part of a $1,012,474 allocation. See details
National Institutes of Health 9/29/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $9,599 Trans-NIH Recovery Act Research Support (B) Tissue specific deletion of netrin-1 during acute lung injury. We are presently generating a floxed netrin-1 mouse model (see letter Ozgene, these mice will be available to us in summer 2009). We will then cross these mice with cre-recombinase mice fo National Institutes of Health 7/16/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $7,488 Trans-NIH Recovery Act Research Support Herein we submit a revision of a model of biobehavioral development that focuses on the origins of individual differences in voluntary alcohol consumption in young socially housed bonnet macaque monkeys. Differences in early maternal care are suggested as
This spending item is part of a $133,366 allocation. See details
National Institutes of Health 7/15/2009
PARTNERSHIPS FOR HEALTHY COMMUNITIES $2,650 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work - The Tri-County Health Department, the largest local health department in Colorado which serves more than a million residents of Adams, Arapahoe and Douglas Counties, will partner with schoo... Show more
This spending item is part of a $10,511,509 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $732 Trans-NIH Recovery Act Research Support The funds will be used to develop, open and analyze three H1N1 studies in HIV-infected populations. The first study will determine the safety and immunogenicity of an H1N1 vaccine in HIV-infected pregnant women. The second study will determine safety an
This spending item is part of a $1,701,287 allocation. See details
National Institutes of Health 11/25/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $0 Trans-NIH Recovery Act Research Support Cholestatic liver diseases are among the most important liver disorders that occur in infants and children, leading to devastating morbidity and accounting for over 70% of liver transplants performed during childhood, posing a major public health burden.
This spending item is part of a $143,500 allocation. See details
National Institutes of Health 3/11/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $0 ARRA Grants for Training in Primary Care Medicine and Dentistry Training and Enhancement The Physician Faculty Development Program in Primary Care is a collaborative program between the Divisions of General Internal Medicine, General Pediatrics and the Department of Family Medicine. The Program iden... Show more
This spending item is part of a $462,171 allocation. See details
Health Resources and Services Administration 7/15/2010
REGENTS OF THE UNIVERSITY OF COLORADO, THE $0 Trans-NIH Recovery Act Research Support Abstract this project aims to establish a Lung Cancer Mutation Consortium (LCMC) consisting of 13 institutions with a major interest in lung cancer and genomic testing of lung cancer as documented by having major NCI grants in lung cancer. The LCMC member
This spending item is part of a $4,894,665 allocation. See details
National Institutes of Health 9/29/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $0 Trans-NIH Recovery Act Research Support We are a group of ten NIH-funded faculty investigators from the INIA-West Consortium; three of us are at the University of Colorado Denver School of Medicine (applicant institution) and seven are at other institutions including the Scripps Research Instit National Institutes of Health 5/13/2010