Recovery Tracker

How Much Stimulus Funding is Going to Your County?

Forsyth County, N.C., funds by Health and Human Services, Department of

Listing $56,150,101.61 in stimulus funds from Health and Human Services, Department of for Forsyth

Note: For some programs where states do not report where money will be distributed across the state, we do not have the allocation for individual counties. Those programs include: Medicaid, unemployment benefits and food stamps. Those amounts are included in the totals for where the state agency receiving that money is located.

Amount refers to both the amount of stimulus funding going toward the project and the face value of the loan.

Recipient Amount Description Federal Dept./Agency Date
WAKE FOREST UNIVERSITY $3,355,055 Trans-NIH Recovery Act Research Support As life expectancy in the United States continues to rise, the maintenance of physical independence among older Americans has emerged as a major clinical and public health priority. Efficient and reliable locomotion, or the ability to move without assista
This spending item is part of a $29,648,216 allocation. See details
National Institutes of Health 9/24/2009
WAKE FOREST UNIVERSITY $2,750,631 Trans-NIH Recovery Act Research Support Illicit drug use is not only a major global health problem, but has also had a profoundly negative social, political, and economic impact that continues to increase in magnitude. Although treatments such as the nicotine patch or methadone have been useful National Institutes of Health 9/25/2009
FORSYTH, COUNTY OF $2,460,160 ARRA Child Care and Development Block Grant ARRA Supplemental Funding for the Child Care and Development Fund (CCDF): Provide child care financial assistance to low-income working families and fund activities to support the quality of child care. Child care subsidy funds were used to fund direct
This spending item is part of a $67,543,134 allocation. See details
Administration for Children and Families 4/09/2009
WAKE FOREST UNIVERSITY $2,422,964 Trans-NIH Recovery Act Research Support Prostate cancer (PCa) is the most common cancer among men in the U.S. One important strategy to address this public health concern is to prevent the disease. Two large randomized clinical trials, The Prostate Cancer Prevention Trial (PCPT) and The Reducti
This spending item is part of a $3,978,770 allocation. See details
National Institutes of Health 9/29/2009
WAKE FOREST UNIVERSITY $2,293,507 Trans-NIH Recovery Act Research Support As life expectancy in the United States continues to rise, the maintenance of physical independence among older Americans has emerged as a major clinical and public health priority. Efficient and reliable locomotion, or the ability to move without assista
This spending item is part of a $29,648,216 allocation. See details
National Institutes of Health 9/24/2009
WAKE FOREST UNIVERSITY $2,139,477 Trans-NIH Recovery Act Research Support Severe asthma, a heterogeneous disease consisting of related clinical phenotypes, generates high levels of morbidity, mortality and health care costs. The complexity and heterogeneity of the disorder have limited clinical advances. However, the NHLBI Seve
This spending item is part of a $3,489,267 allocation. See details
National Institutes of Health 9/25/2009
WAKE FOREST UNIVERSITY $2,000,000 Trans-NIH Recovery Act Research Support New Cyclotron for Translational PET Imaging Project Summary: We herein request for a replacement Cyclotron for the Center for Biomolecular Imaging (CBI) program at WFUHS. The CBI is a centralized imaging resource at our institution that supports the tran National Institutes of Health 4/28/2009
WAKE FOREST UNIVERSITY $1,985,839 Trans-NIH Recovery Act Research Support Medical imaging is a critical and expensive component of health care with a cost of $100 billion or $350 per person per year. Health information technology (HIT) is proposed as a means to reduce costs and improve health through more efficient and coordina
This spending item is part of a $2,033,637 allocation. See details
National Institutes of Health 9/25/2009
WAKE FOREST UNIVERSITY $1,490,062 ARRA - Health Information Technology Extension Program American Recovery and Reinvestment Act of 2009, Health Information Technology Ex Project goals, objectives, overall approach Meaningful use of health information technology (HIT) is key to improving the quality and value of health care, but pro... Show more
This spending item is part of a $14,443,487 allocation. See details
Health and Human Services, Department of 2/08/2010
WAKE FOREST UNIVERSITY $1,434,256 Trans-NIH Recovery Act Research Support This supplemental award provides funding to support the hiring of a hematologist/oncologist with an acute myelogenous leukemia (AML) focus. This award will support the recruitment of a physician-scientist with outstanding laboratory and clinical skills. National Institutes of Health 9/23/2009
WAKE FOREST UNIVERSITY $1,422,967 Trans-NIH Recovery Act Research Support Adequate housing is a fundamental human right. However, the limited research that has been conducted demonstrates that inadequate housing is the most basic of all of the unjust and inequitable conditions that farmworkers in North Carolina and the southeas
This spending item is part of a $1,783,650 allocation. See details
National Institutes of Health 9/03/2009
WAKE FOREST UNIVERSITY $1,153,328 Trans-NIH Recovery Act Research Support The long-term goal of this research project is to improve the efficacy of anti-nicotine vaccination/immunotherapy for smoking cessation. The proposal relates to the special interest of NIDA in RFAOD- 09-004: G?Nicotine and Tobacco ResearchG? and addresses
This spending item is part of a $2,583,504 allocation. See details
National Institutes of Health 9/30/2009
WOODBINE AGENCY, INC., THE $1,150,000 ARRA - Prevention and Wellness--State Territories and Pacific Islands American Recovery and Reinvestment Act (ARRA) funding will support initiatives to prevent and reduce obesity and tobacco use and improve the health of millions of North Carolinians. The North Carolina Division of Public Health and... Show more
This spending item is part of a $3,000,000 allocation. See details
Centers for Disease Control and Prevention 2/06/2010
WAKE FOREST UNIVERSITY $966,871 The Systolic Blood Pressure Intervention Trial (SPRINT)-Senior ARRA expansion is designed to test the SPRINT intervention in participants who are ? 75 years of age. Approximately 3,250 of the 9,250 SPRINT participants are expected to be age 75 or older. I
This spending item is part of a $2,392,562 allocation. See details
National Institutes of Health 9/24/2010
WAKE FOREST UNIVERSITY $946,933 Trans-NIH Recovery Act Research Support Human pluripotent stem cells (hPSCs) will be crucial for the development of regenerative therapies, especially when autologous specialized cells cannot be obtained in sufficient quantity. Despite great promise, pluripotent embryonic stem (ES) cells have s National Institutes of Health 9/22/2009
EXPERIMENT IN SELF-RELIANCE, INC. $945,247 ARRA - Community Services Block Grant North Carolina's ARRA Supplemental Funding for the Community Services Block Grant (CSBG) Program funds were allocated to a network of eligible organizations (Community Action Agencies) to support employment related services that primarily created and sust
This spending item is part of a $26,243,124 allocation. See details
Administration for Children and Families 4/10/2009
WAKE FOREST UNIVERSITY $933,934 Trans-NIH Recovery Act Research Support The Forsyth County Healthy Living Collaborative (FCHL Collaborative) is a partnership among Wake Forest University Health Sciences (WFUHS), Communities Helping All Neighbors Gain Empowerment (CHANGE), the Forsyth County Department of Public Health (FCDPH)
This spending item is part of a $999,346 allocation. See details
National Institutes of Health 8/13/2010
WAKE FOREST UNIVERSITY $874,913 The Systolic Blood Pressure Intervention Trial (SPRINT)-Senior ARRA expansion is designed to test the SPRINT intervention in participants who are ? 75 years of age. Approximately 3,250 of the 9,250 SPRINT participants are expected to be age 75 or older. I
This spending item is part of a $2,671,616 allocation. See details
National Institutes of Health 9/24/2010
WAKE FOREST UNIVERSITY $847,059 Trans-NIH Recovery Act Research Support Genetic alterations and epigenetic modifications are hallmarks of cancers, including prostate cancer (PCa). Understanding factors associated with the progression of PCa will have a significant impact on management and treatment of the disease. We hypothes
This spending item is part of a $1,116,642 allocation. See details
National Institutes of Health 8/12/2009
WAKE FOREST UNIVERSITY $792,106 Trans-NIH Recovery Act Research Support High avidity CD8+ T cells are known to be the most effective mediators of viral clearance. Thus understanding how avidity is controlled following viral infection is of critical importance for designing optimally effective therapeutics and vaccines. Functi National Institutes of Health 5/30/2009
WAKE FOREST UNIVERSITY $771,031 Trans-NIH Recovery Act Research Support This project aims to develop methods for analyzing complex interactions in longitudinal data collected from biomedical studies that contain a strong social and behavioral component. Of special interest are data collected on elderly populations, within whi
This spending item is part of a $854,707 allocation. See details
National Institutes of Health 8/17/2009
WINSTON-SALEM STATE UNIVERSITY (INC) $761,533 ARRA - Scholarships for Disadvantaged Students The Scholarships for Disadvantaged Students program provides scholarships to full-time, financially needy students from disadvantaged backgrounds, enrolled in health professions and nursing programs. Participating schools are responsible for selecting sc... Show more Health Resources and Services Administration 9/03/2009
WAKE FOREST UNIVERSITY $740,000 Trans-NIH Recovery Act Research Support Loss of functional skeletal muscle due to congenital and acquired conditions, such as traumatic injury, tumor excision, etc., produces a physiological deficit for which there is still no effective clinical treatment. Tissue engineering of skeletal muscle National Institutes of Health 9/01/2009
WAKE FOREST UNIVERSITY $666,000 Trans-NIH Recovery Act Research Support About 10 percent of American families are affected by infertility. Among which, one third of these cases are due to female factors, one third to male factors, and the remainder are a mixture or have unknown causes. Mitochondrial dysfunction is responsible National Institutes of Health 7/28/2009
WAKE FOREST UNIVERSITY $654,195 Trans-NIH Recovery Act Research Support Description of Overall Purpose-The long-term goal of the proposed research is to further develop and understand the nitric oxide (NO) and nitroxyl (HNO), the one-electron reduced form of NO, producing reactions of C-nitroso compounds (1, Scheme 1). Some National Institutes of Health 6/16/2009
WAKE FOREST UNIVERSITY $652,800 Trans-NIH Recovery Act Research Support This project is based on a multidisciplinary, international collaboration to study the role of cannabinoid receptors and the endocannabinoid system in behavior, pharmacology and physiology of cognitive function. The collaboration entails an unprecedented
This spending item is part of a $702,800 allocation. See details
National Institutes of Health 7/16/2009
WAKE FOREST UNIVERSITY $598,465 Trans-NIH Recovery Act Research Support Look AHEAD is a multi-center randomized clinical trial to determine the long-term impact of weight loss on cardiovascular morbidity and mortality in over 5000 overweight individuals with type 2 diabetes. Participants were randomly assigned to an intensiv National Institutes of Health 9/29/2009
WAKE FOREST UNIVERSITY $534,190 Trans-NIH Recovery Act Research Support Interaction of germline and somatic changes in PCa progression Abstract Recent successes in discovering germline variants associated with prostate cancer (PCa) risk is encouraging. However, whether these risk variants play role in PCa progression is uncle
This spending item is part of a $819,892 allocation. See details
National Institutes of Health 7/17/2009
WAKE FOREST UNIVERSITY $479,128 Trans-NIH Recovery Act Research Support We have demonstrated that epinephrine at concentrations observed during stress induces PKA-dependent phosphorylation of the pro-apoptotic protein BAD and protects prostate cancer cells from apoptosis (JBC2007 in 'appendix'). Furthermore, recent in vivo ex
This spending item is part of a $701,622 allocation. See details
National Institutes of Health 8/31/2009
WAKE FOREST UNIVERSITY $451,012 Trans-NIH Recovery Act Research Support The liver has an enormous capacity to regenerate, as demonstrated by the 2/3 partial hepatectomy model in rodents. A stem cell compartment within the liver is activated when mature hepatocytes are unable to perform their role in this process. The overarch National Institutes of Health 9/30/2010
WAKE FOREST UNIVERSITY $429,166 Trans-NIH Recovery Act Research Support This application entitled, 'Discovering Pathways of Functional Decline: A GWAS Approach' addresses the challenge area (08): Genomics and the specific challenge topic, 08-AG-101: Genetic factors affecting rates of change in disease risk factors with age. T
This spending item is part of a $814,020 allocation. See details
National Institutes of Health 9/24/2009
WAKE FOREST UNIVERSITY $413,301 Trans-NIH Recovery Act Research Support End stage renal disease (ESRD), one of the most serious and costly complications of systemic lupus erythematosus (SLE), occurs in a sub-set of patients with SLE-related renal involvement. Factors predisposing to ESRD presumably include both genetics and
This spending item is part of a $3,350,000 allocation. See details
National Institutes of Health 9/28/2009
NEUROSCIENCE RESEARCH INSTITUTE OF NORTH CAROLINA $412,500 Trans-NIH Recovery Act Research Support The project aims to determine neuronal activity that is predictive of seizures in rat models of spontaneous seizures induced in the amygdala of the brain. Neuron ensembles will be recorded in amygdala and hippocampus. Pattern recognition techniques will National Institutes of Health 5/15/2009
WAKE FOREST UNIVERSITY $410,715 Trans-NIH Recovery Act Research Support As life expectancy in the United States continues to rise, the maintenance of physical independence among older Americans has emerged as a major clinical and public health priority. Efficient and reliable locomotion, or the ability to move without assista
This spending item is part of a $29,648,216 allocation. See details
National Institutes of Health 9/24/2009
WAKE FOREST UNIVERSITY $407,000 Trans-NIH Recovery Act Research Support We propose this R21 feasibility study to assess factors related to recruiting rural and minority parents to a study that would involve themselves and their children in an assessment of their behavioral, home environmental and genetic characteristics. Spe National Institutes of Health 5/14/2009
WAKE FOREST UNIVERSITY $407,000 Trans-NIH Recovery Act Research Support Systemic lupus erythematosus (SLE, lupus) is a complex systemic autoimmune disease characterized by various immunological abnormalities, including an imbalance between type 1 and type 2 T cells that contributes to skewed cytokine production. The initial s National Institutes of Health 7/17/2009
WAKE FOREST UNIVERSITY $407,000 Trans-NIH Recovery Act Research Support IL-4- and IL-13- producing type 2 T cells, are critical for the development of atopy and contribute to asthma pathogenesis by a variety of mechanisms. PGD2, a prostaglandin produced predominantly by mast cells, is involved in chemoattraction of eosinophil National Institutes of Health 5/21/2009
WAKE FOREST UNIVERSITY $407,000 Trans-NIH Recovery Act Research Support Children with complex chronic conditions (CCC) receive care from diverse medical, educational and social service providers through various agencies for a prolonged period of time. Coordination of care between agencies serving these children is lacking, re National Institutes of Health 8/27/2009
WAKE FOREST UNIVERSITY $405,903 Trans-NIH Recovery Act Research Support High grade malignant gliomas are the leading cause of primary brain cancer deaths, afflicting close to 20,000 patients annually in the United States alone. Targeting tumor-specific molecular biomarkers offers the potential to deliver large amounts of ther National Institutes of Health 9/30/2009
WAKE FOREST UNIVERSITY $393,646 Trans-NIH Recovery Act Research Support Our society must make difficult policy decisions about complex biomedical research and treatment issues without the scientific understanding or expertise to critically evaluate these issues. So, while scientists understanding of the effects of addictive d
This spending item is part of a $531,010 allocation. See details
National Institutes of Health 8/14/2009
WAKE FOREST UNIVERSITY $376,962 Trans-NIH Recovery Act Research Support The experiments in this project are designed to generate improved vaccines against HIV-1 based on recombinant vesicular stomatitis viruses. The vaccine vectors developed in this project will be compared with recombinant RV and NDV vectors generated in pro
This spending item is part of a $2,676,279 allocation. See details
National Institutes of Health 9/01/2009
WAKE FOREST UNIVERSITY $370,000 Trans-NIH Recovery Act Research Support Reprogrammed expression of sets of inflammatory genes occurs during severe systemic inflammation (SSI). The gene silencing component of SSI reprogramming represses transcription of acute proinflammatory genes like TNF? and IL-1? to generate clinically rel National Institutes of Health 6/04/2009
WAKE FOREST UNIVERSITY $358,160 Trans-NIH Recovery Act Research Support A better understanding of the limitations of current physical assessment measures is needed. Both random and systematic errors in an assessment method can have a large impact on estimating the relationship between physical activity and disease. By using a National Institutes of Health 5/21/2009
WAKE FOREST UNIVERSITY $356,655 Trans-NIH Recovery Act Research Support The 3'??5' deoxyribonucleases are essential enzymes in DNA metabolism that catalyze excision of nucleotides from the 3' ends of DNA to prepare these 3' termini for subsequent steps during DNA processing. The long term goal of this project is to understand National Institutes of Health 8/03/2009
WAKE FOREST UNIVERSITY $354,948 Trans-NIH Recovery Act Research Support One of the brain's remarkable capabilities is the ability to integrate information from very different sources to produce a coherent picture of the external world. This enhances its ability to detect, localize and identify environmental events. There is n National Institutes of Health 9/23/2009
WAKE FOREST UNIVERSITY $340,400 Trans-NIH Recovery Act Research Support Design of new treatment agents for drug abuse The development of effective medications for the treatment of drug addiction disorders is of great importance to society. Great advances have been made in the treatment of many CNS diseases that were previou
This spending item is part of a $772,650 allocation. See details
National Institutes of Health 7/16/2009
WINSTON-SALEM STATE UNIVERSITY FOUNDATION, INCORPORATED $309,231 Trans-NIH Recovery Act Research Support WSSU seeks to establish a Minority Access to Research Careers Student Training in Academic Research (MARC U*STAR) program to promote advancement of minorities who pursue advanced research careers in biomedical science. WSSU proposes to accomplish the foll National Institutes of Health 7/15/2009
WAKE FOREST UNIVERSITY $305,356 Trans-NIH Recovery Act Research Support This application proposes the acquisition of resources (personnel and equipment) that will enhance and accelerate the translational activities conducted in two NCRR-supported Animal and Biological Materials Resources (ABMR): 1) the Vervet Research Colony National Institutes of Health 8/20/2009
WAKE FOREST UNIVERSITY $300,000 ARRA ? Equipment to Enhance Training for Health Professionals Equipment requested will expand training capabilities. The Patient-Centered Medical Home (PCMH) model of integrated team-based care fosters partnerships between patients and their personal physicians. We seek to support interprofessional... Show more Health Resources and Services Administration 9/03/2010
WAKE FOREST UNIVERSITY $294,958 Trans-NIH Recovery Act Research Support This competitive revision of R21 AT004234-01 Effectiveness of Integral Yoga on Objective and Subjective Menopausal Hot Flashes is in response to NOT-OD-09-058: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. Th National Institutes of Health 9/16/2009
WAKE FOREST UNIVERSITY $289,039 Trans-NIH Recovery Act Research Support This research seeks to determine the role extracellular matrix (ECM) plays in the aging of skeletal muscle. The loss of skeletal muscle mass and strength that occurs during the aging process represents a major health issue facing a growing elderly populat
This spending item is part of a $333,741 allocation. See details
National Institutes of Health 7/21/2009
WAKE FOREST UNIVERSITY $285,991 Trans-NIH Recovery Act Research Support Decisions about where to look within a typical visual scene are governed by the relative salience of individual stimuli and current behavioral objectives. To date, the majority of studies examining the cognitive control of visual orienting have targeted f National Institutes of Health 9/30/2009
WAKE FOREST UNIVERSITY $272,762 Trans-NIH Recovery Act Research Support This P20 proposal presents a research and educational partnership between the Wake Forest University Comprehensive Cancer Center (WFUCCC) and the Departments of Biology and Chemistry of North Carolina Agricultural and Technical University (NC A&T). The ob National Institutes of Health 9/28/2009
WAKE FOREST UNIVERSITY $271,207 Trans-NIH Recovery Act Research Support Despite the success of lipid lowering drugs for the prevention of coronary artery disease and myocardial infarction, atherosclerosis remains the most common cause of disease-related death in the Western world and in developing countries. We and others hav National Institutes of Health 7/16/2009
WINSTON-SALEM STATE UNIVERSITY FOUNDATION, INCORPORATED $269,903 ARRA - Scholarships for Disadvantaged Students The Scholarships for Disadvantaged Students program provides scholarships to full-time, financially needy students from disadvantaged backgrounds, enrolled in health professions and nursing programs. Participating schools are responsible for selecting sc... Show more Health Resources and Services Administration 6/14/2010
FAMILY SERVICES, INC. $259,322 ARRA - Head Start COLA Project - 1. Fund an increase in the contributions to the retirement plan. 2. fund increased costs of building operations. Administration for Children and Families 7/13/2009
WAKE FOREST UNIVERSITY $257,340 Trans-NIH Recovery Act Research Support The cellular mechanisms that mediate the intoxicating and reinforcing effects of ethanol are not completely understood. However, considerable evidence supports the hypothesis that increased mesolimbic DA system activity is one of the important components National Institutes of Health 9/21/2009
WAKE FOREST UNIVERSITY $238,378 Trans-NIH Recovery Act Research Support Diabetes is a risk factor for cerebrovascular disease, cognitive impairment, and related dementia. Data derived from populations suggest that several comorbidities of diabetes increase the risk for cognitive impairment, structural brain changes associated National Institutes of Health 8/17/2009
WAKE FOREST UNIVERSITY $228,363 Trans-NIH Recovery Act Research Support Our programmatic goal is to provide for an integrated career development pathway in clinical aging research for both physician and non-physicians. We are requesting funds to support establishment of a geriatric fellow / post-doctoral training program desi National Institutes of Health 5/21/2009
WAKE FOREST UNIVERSITY $227,195 Trans-NIH Recovery Act Research Support Dendritic cells (DC) are essential to the development of protective immunity to a number of infectious pathogens. These cells alert the adaptive immune system to the presence of pathogenic invaders and activate these cells to clear infections. To stimulat
This spending item is part of a $394,694 allocation. See details
National Institutes of Health 5/21/2009
WAKE FOREST UNIVERSITY $226,905 Trans-NIH Recovery Act Research Support EVE is a consortium comprised of all U.S. investigators who have conducted genome-wide association studies (GWAS) of asthma and whose main objective is to combine results of individual studies to increase the overall power to identify asthma-susceptibilit
This spending item is part of a $7,375,208 allocation. See details
National Institutes of Health 9/25/2009
WAKE FOREST UNIVERSITY $222,494 Trans-NIH Recovery Act Research Support We have demonstrated that epinephrine at concentrations observed during stress induces PKA-dependent phosphorylation of the pro-apoptotic protein BAD and protects prostate cancer cells from apoptosis (JBC2007 in 'appendix'). Furthermore, recent in vivo ex
This spending item is part of a $701,622 allocation. See details
National Institutes of Health 8/31/2009
WAKE FOREST UNIVERSITY $215,305 Trans-NIH Recovery Act Research Support Recommendations for more effective long-term weight loss strategies may need to consider the role of gender differences. If, as shown in female vs. male animal models, negative energy balance resulting in weight loss results in greater compensatory reduct
This spending item is part of a $362,622 allocation. See details
National Institutes of Health 9/18/2009
WAKE FOREST UNIVERSITY $214,186 Trans-NIH Recovery Act Research Support Carbon nanotubes are graphene sheets of sp2 bonded atoms rolled seamlessly into a tube of 1.5 - 20 nm in diameter. This material has unique properties, including the ability to generate heat when stimulated with infrared light. We have used the features o
This spending item is part of a $267,798 allocation. See details
National Institutes of Health 9/08/2009
WAKE FOREST UNIVERSITY $212,229 Trans-NIH Recovery Act Research Support Overweight and obesity are epidemic in the United States with over 2/3 of American adults having a body mass index of > 25 kg/m.2 Obesity and physical inactivity represent the second leading cause of preventable death nationally from cancer, cardiovascula National Institutes of Health 9/14/2009
WAKE FOREST UNIVERSITY $209,224 Trans-NIH Recovery Act Research Support The proposed research study responds to an unmet need for the successful implementation and dissemination of evidence-based tobacco cessation care for the uninsured. The overall intent of this research is to ultimately close the gap between research disco
This spending item is part of a $370,064 allocation. See details
National Institutes of Health 8/11/2009
WAKE FOREST UNIVERSITY $208,705 Trans-NIH Recovery Act Research Support We are applying for funds to replace the ThermoFisher single quadrupole Trace MS GC mass spectrometer that was installed in 1999 and that is used to quantify small volatile lipids. In the last year about 47% of all analyses were performed on the Trace MS. National Institutes of Health 4/22/2010
TENSIVE CONTROLS, INC. $199,345 Trans-NIH Recovery Act Research Support Cachexia or ?cachexia-anorexia syndrome? is a consequence of many disease states, including malignancies, bacterial and viral infections, and inflammatory conditions (e.g. rheumatoid arthritis), as well as treatments for these conditions (e.g. chemo National Institutes of Health 6/18/2010
TENSIVE CONTROLS, INC. $199,345 This project has the long-term goal of developing melanocortin receptor (MCR) antagonists as therapeutic drugs for cachexia. Cachexia, characterized by a lack of appetite and a loss of lean body mass, is a frequent complication of malignancy, infec National Institutes of Health 6/18/2010
WAKE FOREST UNIVERSITY $188,795 Trans-NIH Recovery Act Research Support This supplement to our project entitled Pericardial Fat and Subclinical and Clinical measures of Coronary Heart Disease (R01 HL085323) aims to accelerate progress on understanding the relation between adiposity around the heart and deaths secondary to cor National Institutes of Health 8/10/2009
WAKE FOREST UNIVERSITY $183,049 Trans-NIH Recovery Act Research Support It is estimated that 3.2 million African Americans aged 20 years or older have T2DM. This represents approximately 13 percent of the AA population and a significant proportion of the more than 20 million Americans believed to be living with diabetes, a di
This spending item is part of a $4,254,196 allocation. See details
National Institutes of Health 7/21/2009
WAKE FOREST UNIVERSITY $181,702 Trans-NIH Recovery Act Research Support It is widely appreciated that reactive oxygen species (ROS) play a major role in the initiation of cancer, and they are also implicated in many cancer therapies, such as ionizing radiation, cisplatin and taxanes. More recently, it has been discovered that National Institutes of Health 8/28/2009
WAKE FOREST UNIVERSITY $179,873 Trans-NIH Recovery Act Research Support The ability of humans to mount an effective immune response declines with age, leaving the elderly susceptible to infectious diseases and cancer. Moreover, vaccines tested in younger individuals are often ineffective in older people. Thus, as new vaccines
This spending item is part of a $270,579 allocation. See details
National Institutes of Health 9/04/2009
WAKE FOREST UNIVERSITY $170,240 Trans-NIH Recovery Act Research Support This Phase I and II application is designed to create and implement programs that better educate students regarding science concepts, the scientific inquiry process, and related careers. The Center of Excellence for Research, Teaching, and Learning (CERTL National Institutes of Health 6/04/2009
WAKE FOREST UNIVERSITY $167,499 Trans-NIH Recovery Act Research Support Dendritic cells (DC) are essential to the development of protective immunity to a number of infectious pathogens. These cells alert the adaptive immune system to the presence of pathogenic invaders and activate these cells to clear infections. To stimulat
This spending item is part of a $394,694 allocation. See details
National Institutes of Health 5/21/2009
WAKE FOREST UNIVERSITY $164,585 Trans-NIH Recovery Act Research Support Although several popular theories postulate that the capacity to engage in multisensory integration is already present at birth, and is largely insensitive to experience, observations from the past grant period suggest quite the opposite. Using midbrain a National Institutes of Health 8/14/2009
WAKE FOREST UNIVERSITY $162,917 Trans-NIH Recovery Act Research Support Pain-related disorders cause an incalculable toll in human suffering and present a significant economic problem. The development of new treatments for these disorders is being hindered by a lack of information about the basic brain mechanisms that support National Institutes of Health 9/28/2009
WAKE FOREST UNIVERSITY $155,882 Trans-NIH Recovery Act Research Support Look AHEAD is a multi-center randomized clinical trial to determine the long-term impact of weight loss on cardiovascular morbidity and mortality in over 5000 overweight individuals with type 2 diabetes. Participants were randomly assigned to an intensiv National Institutes of Health 9/28/2009
WAKE FOREST UNIVERSITY $152,066 Trans-NIH Recovery Act Research Support This program is designed to provide interim positions for under-represented minority students and students from disadvantaged groups with post- baccalaureate degrees interested in pursuing graduate education. The focus is on research training under a stro National Institutes of Health 9/15/2009
WAKE FOREST UNIVERSITY $150,928 Trans-NIH Recovery Act Research Support The overall goal of this proposal is to understand the contribution of metabolic, behavioral and diabetes-specific risk factors to the development of cardiovascular sub-clinical abnormalities in adolescents and young adults with T1D, as compared to non-di
This spending item is part of a $1,522,341 allocation. See details
National Institutes of Health 9/21/2009
WAKE FOREST UNIVERSITY $150,000 Trans-NIH Recovery Act Research Support The goal of the Gastroparesis Clinical Reserach Consortium (GpCRC) is to perform research in gastroparesis and provide an infrastructure that can rapidly and efficiently conduct clinical trials to improve treatment of gastroparesis. At Wake Forest, we hav National Institutes of Health 9/15/2009
WAKE FOREST UNIVERSITY $148,000 Trans-NIH Recovery Act Research Support Beta-agonists are the most common medication used for treatment of acute asthma attacks. Inter-individual responses to beta-agonist are variable, and there is strong evidence that genetics play an important role in determining these inter-individual respo National Institutes of Health 6/18/2009
WAKE FOREST UNIVERSITY $147,317 Trans-NIH Recovery Act Research Support Recommendations for more effective long-term weight loss strategies may need to consider the role of gender differences. If, as shown in female vs. male animal models, negative energy balance resulting in weight loss results in greater compensatory reduct
This spending item is part of a $362,622 allocation. See details
National Institutes of Health 9/18/2009
WAKE FOREST UNIVERSITY $144,541 Trans-NIH Recovery Act Research Support Research into the role of neurotransmitter systems in the reinforcing effects of cocaine has traditionally focused on monoamines; however recent studies in rodents indicate a strong involvement of glutamatergic mechanisms, particularly during abstinence. National Institutes of Health 6/05/2009
WAKE FOREST UNIVERSITY $135,601 Trans-NIH Recovery Act Research Support Oncolytic ElB-55K-mutant adenoviruses have entered phase III clinical trials. However, the basis for their selective replication in tumor cells is poorly understood. Work of this lab has shown that ElB-55K-mutant viruses selectively replicate in and kill National Institutes of Health 8/27/2009
WAKE FOREST UNIVERSITY $132,133 Trans-NIH Recovery Act Research Support Aging is accompanied by a decline in immune responsiveness that renders older adults highly susceptible to infectious diseases, and immunization vs. vaccine preventable illness such as influenza is less effective in seniors. A recently identified, vaccine
This spending item is part of a $360,894 allocation. See details
National Institutes of Health 5/20/2009
WAKE FOREST UNIVERSITY $126,374 Trans-NIH Recovery Act Research Support As life expectancy in the US continues to rise, the maintenance of independence among older Americans has emerged as a major clinical and public health priority. Efficient and reliable locomotion, or the ability to move without assistance, is a fundamenta
This spending item is part of a $1,524,000 allocation. See details
National Institutes of Health 3/31/2010
WAKE FOREST UNIVERSITY $125,878 Trans-NIH Recovery Act Research Support Herein we submit a revision of a model of biobehavioral development that focuses on the origins of individual differences in voluntary alcohol consumption in young socially housed bonnet macaque monkeys. Differences in early maternal care are suggested as
This spending item is part of a $133,366 allocation. See details
National Institutes of Health 7/15/2009
WAKE FOREST UNIVERSITY $120,387 Trans-NIH Recovery Act Research Support A decrement in spatial learning ability in normal aging has consistently been correlated with blunted receptor signaling mediated through the muscarinic and metabotropic glutamate receptor-G1q/11 signaling transduction system. The role of G1q/11-mediated National Institutes of Health 4/29/2009
NORTHWEST PIEDMONT COUNCIL OF GOVERNMENT $111,118 Aging Congregate Nutrition Services for States ARRA provided funding for Congregate Nutrition Services. Established in 1972 under the Older Americans Act, the program provides meals to older americans in congregate facilities such as senior centers, adult day centers, and faith-based settings.
This spending item is part of a $1,855,370 allocation. See details
Administration on Aging 3/18/2009
WAKE FOREST UNIVERSITY $107,904 Trans-NIH Recovery Act Research Support DESCRIPTION: This is an application for a 2 year administrative supplement to provide technical support for 5 K08 GM083154-02. Funds are requested to retain a technician to maintain the productivity and accelerated pace of the research project. The appli National Institutes of Health 9/30/2009
WAKE FOREST UNIVERSITY $104,242 Trans-NIH Recovery Act Research Support Primary hyperoxaluria is a rare, genetic disorder that results from an excessive endogenous synthesis of oxalate. Glyoxylate reductase (GR) is a key enzyme in this biosynthetic pathway, converting glyoxylate, the main precursor of oxalate, to glycolate an National Institutes of Health 11/28/2009
WAKE FOREST UNIVERSITY $100,640 Trans-NIH Recovery Act Research Support This application targets the millions of patients suffering from bladder disease/dysfunction related to congenital anomalies, cancer, infection, inflammation or lesions of the central or peripheral nervous system. Regardless of etiology, in all cases thes National Institutes of Health 9/03/2009
WAKE FOREST UNIVERSITY $100,001 Trans-NIH Recovery Act Research Support The metallochemistry and molecular biology of iron converge in the study of ferritin structure and function. Ferritin is an iron binding protein whose regulation, once thought to be responsive only to changes in cellular iron content, has National Institutes of Health 9/21/2009
WAKE FOREST UNIVERSITY $99,895 Trans-NIH Recovery Act Research Support Progressive cognitive impairment occurs in up to 50% of primary and metastatic brain tumor patients who survive 6 months or longer after treatment with partial or whole-brain irradiation (WBI); ~200,000 patients/year receive these treatments. A growing bo National Institutes of Health 8/31/2009
WAKE FOREST UNIVERSITY $87,136 Trans-NIH Recovery Act Research Support One of the most compelling and unresolved issues of visual processing is the role of the massive cortical feedback that occurs in a number of sites in the visual system. Activation of this feedback is thought to underlie processes such as attention. It ma National Institutes of Health 12/14/2009
WAKE FOREST UNIVERSITY $84,616 Trans-NIH Recovery Act Research Support As life expectancy in the US continues to rise, the maintenance of independence among older Americans has emerged as a major clinical and public health priority. Efficient and reliable locomotion, or the ability to move without assistance, is a fundamenta
This spending item is part of a $1,524,000 allocation. See details
National Institutes of Health 3/31/2010
WAKE FOREST UNIVERSITY $84,122 Trans-NIH Recovery Act Research Support The funds provided by this Revision grant are being used to accelerate the development of a novel clinical candidate for the treatment of osteoarthritis (OA), a disease that currently affects 22% of the US population but has no effective treatment. We wi
This spending item is part of a $334,600 allocation. See details
National Institutes of Health 9/29/2009
WAKE FOREST UNIVERSITY $83,620 Trans-NIH Recovery Act Research Support Kidney stone disease is a significant health problem that consumes billions of dollars annually in health care costs and lost productivity. The bulk of these stones consist primarily of calcium oxalate. The amount of calcium and oxalate in urine are thus National Institutes of Health 3/29/2010
WAKE FOREST UNIVERSITY $82,141 Trans-NIH Recovery Act Research Support The overall goal of the project is to validate specific protein biomarkers for amyotrophic lateral sclerosis (ALS). ALS is a fatal motor neuron disease that can strike adults of any age, yet we know little about its causes and cannot rapidly diagnose
This spending item is part of a $876,706 allocation. See details
National Institutes of Health 9/21/2009
WAKE FOREST UNIVERSITY $81,551 Trans-NIH Recovery Act Research Support This proposal is based on two remarkable findings from our lab. First, complement neutralizes the closely related paramyxoviruses Simian Virus 5 (SV5) and Mumps Virus (MuV), but by distinct mechanisms involving formation of massive SV5 aggregates versus c National Institutes of Health 5/10/2010
WAKE FOREST UNIVERSITY $80,827 Trans-NIH Recovery Act Research Support Research in this lab and others has provided evidence for an important role for expression of glutathione S-transferases (GSTs) (Phase II detoxification) in normal cellular defenses against reactive electrophilic metabolites of carcinogens, and as part of National Institutes of Health 9/02/2009
WAKE FOREST UNIVERSITY $80,000 Trans-NIH Recovery Act Research Support The robust regeneration potential of fetal tissue suggests that developmental biology may help guide strategies for tissue regeneration in adults. Decreases in regenerative capacity post-utero and with increasing age are likely due to multiple factors, ho
This spending item is part of a $1,274,015 allocation. See details
National Institutes of Health 9/09/2009
WAKE FOREST UNIVERSITY $74,000 Trans-NIH Recovery Act Research Support Every year as many as 200,000 patients receive whole brain irradiation (WBI). Most of these patients are treated not for primary brain tumors, but for brain metastases from melanomas, breast cancer or lung cancer that increase in middle age. As patient su National Institutes of Health 8/31/2009
WAKE FOREST UNIVERSITY $70,670 Trans-NIH Recovery Act Research Support The basic functional of the auditory system is to allow listeners to detect signals in quiet as well as noisy environments. The ability to detect sounds in noisy environments is compromised in the elderly and the hearing impaired. The representation of si National Institutes of Health 7/17/2009
WAKE FOREST UNIVERSITY $69,901 Trans-NIH Recovery Act Research Support Exercise intolerance due to diastolic heart failure (DHF) is a major cause of disability among older Americans. However, relatively little is known regarding the pathophysiology and potential treatment of this pivotal outcome. Several lines of evidence su National Institutes of Health 9/11/2009
WAKE FOREST UNIVERSITY $68,720 Trans-NIH Recovery Act Research Support Flexible endoscopic evaluation of swallowing (FEES) has been available, since approximately 1988, to assess patient swallowing function and determine appropriate oral intake. At this stage, FEES is not a novel diagnostic tool; however, what is novel are t National Institutes of Health 7/17/2009
WAKE FOREST UNIVERSITY $55,167 Trans-NIH Recovery Act Research Support Intrauterine complications (i.e, perinatal asphyxia, prenatal immune activation and cesarean delivery) are a recognized risk factor for the emergence of later neuropsychiatric disorders. These disorders are characterized by hyperdopaminergic function, and National Institutes of Health 7/21/2010
NORTHWEST PIEDMONT COUNCIL OF GOVERNMENT $54,704 Aging Home-Delivered Nutrition Services for States ARRA provided funding for Home-Delivered Nutrition Services. Established in 1978 under the Older Americans Act, the program provides meals to seniors who are homebound.
This spending item is part of a $913,413 allocation. See details
Administration on Aging 3/18/2009
WAKE FOREST UNIVERSITY $54,659 Trans-NIH Recovery Act Research Support Phagocytic NADPH oxidase (Phox) is critically important for generating reactive oxygen species with microbicidal activity. Recently, nonphagocytic NADPH oxidase (Nox) isoforms have been identified which generate reactive oxygen species that function in si National Institutes of Health 6/28/2010
WAKE FOREST UNIVERSITY $54,000 Trans-NIH Recovery Act Research Support This ongoing project previously demonstrated linkage of type 2 diabetes (T2DM) to chromosome 1q21-q24 in Caucasians, and more recently in African American subjects. Data from the last funding period show convincingly that although replicating well across National Institutes of Health 3/14/2010
WAKE FOREST UNIVERSITY $53,612 Trans-NIH Recovery Act Research Support Carbon nanotubes are graphene sheets of sp2 bonded atoms rolled seamlessly into a tube of 1.5 - 20 nm in diameter. This material has unique properties, including the ability to generate heat when stimulated with infrared light. We have used the features o
This spending item is part of a $267,798 allocation. See details
National Institutes of Health 9/08/2009
WAKE FOREST UNIVERSITY $51,983 Trans-NIH Recovery Act Research Support Alcohol abuse continues to be a major problem in the United States with an estimated 14 million adults meeting the clinical criteria for a diagnosis of alcohol abuse or alcoholism at an estimated cost of $185 billion. Chronic alcohol exposure has been sho National Institutes of Health 7/13/2009
WAKE FOREST UNIVERSITY $47,998 Trans-NIH Recovery Act Research Support This grant proposal offers an effective approach to tackle fecal incontinence. We were able to successfully implant bioengineered rings that were constructed from IAS smooth muscle cells and neuronal precursor cells. In essence we have developed intrinsic National Institutes of Health 9/20/2011
WAKE FOREST UNIVERSITY $47,689 Trans-NIH Recovery Act Research Support This supplemental award provides funding to support the Adoption of New Technologies for Remote Data Capture & Protocol Authoring (ADOPT) ARRA Program. ADOPT is an NCI initiative funded through ARRA. ADOPT is intended to improve the efficiency and effec National Institutes of Health 9/21/2009
WAKE FOREST UNIVERSITY $46,500 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Primary vesicoureteral reflux (VUR) is a common problem, occurring [sic] in 8-50% of children with urinary tract infection (UTI). It has the potential for causing irreparable renal damage, particularly [sic] in younge
This spending item is part of a $267,999 allocation. See details
National Institutes of Health 8/18/2009
WAKE FOREST UNIVERSITY $38,766 Trans-NIH Recovery Act Research Support Diabetes mellitus is a growing problem worldwide. In the US it affects over 18 million people and results in annual health care costs exceeding $130 billion. Insulin therapy of Type 1 diabetes, and in advanced cases of Type 2 diabetes, does not prevent se National Institutes of Health 7/17/2009
Grant Neighborhood Program $34,543 Trans-NIH Recovery Act Research Support The Forsyth County Healthy Living Collaborative (FCHL Collaborative) is a partnership among Wake Forest University Health Sciences (WFUHS), Communities Helping All Neighbors Gain Empowerment (CHANGE), the Forsyth County Department of Public Health (FCDPH)
This spending item is part of a $999,346 allocation. See details
National Institutes of Health 8/13/2010
WAKE FOREST UNIVERSITY $34,445 Trans-NIH Recovery Act Research Support Influenza epidemic control is an important public health priority, and the application of isolation, vaccination, and drug treatment measures to control influenza is based on an incomplete understanding of influenza virus epidemiology. Several limited stu National Institutes of Health 9/29/2010
WAKE FOREST UNIVERSITY $33,953 Trans-NIH Recovery Act Research Support This project aims to develop methods for analyzing complex interactions in longitudinal data collected from biomedical studies that contain a strong social and behavioral component. Of special interest are data collected on elderly populations, within whi
This spending item is part of a $854,707 allocation. See details
National Institutes of Health 8/17/2009
North Carolina Association of Free Clinics $31,263 Trans-NIH Recovery Act Research Support The proposed research study responds to an unmet need for the successful implementation and dissemination of evidence-based tobacco cessation care for the uninsured. The overall intent of this research is to ultimately close the gap between research disco
This spending item is part of a $370,064 allocation. See details
National Institutes of Health 8/11/2009
WAKE FOREST UNIVERSITY $31,262 Trans-NIH Recovery Act Research Support Description of overall purpose. The overall purpose of the administrative supplement grant is to increase the scientific value of its parent grant (R15 EB009535-01) by involving 3 additional undergraduates and 1 new high school teacher in our research. National Institutes of Health 6/16/2009
WAKE FOREST UNIVERSITY $30,964 Trans-NIH Recovery Act Research Support RFA-OD-09-004 Recovery Act Limited Competition for NIH Grants: Research and Research Infrastructure G?Grand OpportunitiesG? (RC2) Large-scale genetics studies on schizophrenia to date have failed to discover a substantial contribution of common genetic va
This spending item is part of a $3,132,972 allocation. See details
National Institutes of Health 9/30/2009
Young Women's Christian Association $30,869 Trans-NIH Recovery Act Research Support The Forsyth County Healthy Living Collaborative (FCHL Collaborative) is a partnership among Wake Forest University Health Sciences (WFUHS), Communities Helping All Neighbors Gain Empowerment (CHANGE), the Forsyth County Department of Public Health (FCDPH)
This spending item is part of a $999,346 allocation. See details
National Institutes of Health 8/13/2010
NORTHWEST PIEDMONT COUNCIL OF GOVERNMENT $26,340 ARRA - Communities Putting Prevention to Work: Chronic Disease Self-Manage In collaboration with the Recovery Act-funded Communities putting Prevention to Work (CPPW) program, this funding will support the deployment of evidenced-based chronic disease self-management programs that empower older peopl... Show more
This spending item is part of a $1,006,573 allocation. See details
Administration on Aging 3/31/2010
WAKE FOREST UNIVERSITY $21,391 Trans-NIH Recovery Act Research Support We propose to utilize the requested resources to support additional personnel to perform supplementary research to confirm and expand upon the scientific discoveries expected in the parent grant. The primary goal of this supplement to K01 AG030506 is to
This spending item is part of a $66,179 allocation. See details
National Institutes of Health 9/11/2009
WAKE FOREST UNIVERSITY $20,138 Trans-NIH Recovery Act Research Support The long term goals of this grant are to test mechanisms of pain transmission in the spinal cord of humans and to test whether experimental pain models in animals and humans predict efficacy of spinal analgesics in clinical pain states. We focus on the sp
This spending item is part of a $207,458 allocation. See details
National Institutes of Health 9/25/2009
WAKE FOREST UNIVERSITY $15,000 Trans-NIH Recovery Act Research Support This award responds to RFA-CA-08-504 which is intended to continue support for Phase 1 and 2 treatment studies in adults with primary central nervous system cancers and to continue the activities that were funded initially under RFA CA-04-001. This single
This spending item is part of a $742,737 allocation. See details
National Institutes of Health 7/17/2009
WAKE FOREST UNIVERSITY $13,225 Trans-NIH Recovery Act Research Support This award allowed the hiring of two highly-qualified undergraduate students interested in public health research. During their eight-week summer experience, the students participated in a variety of activities associated with the parent grant G?Measuring National Institutes of Health 5/29/2009
WAKE FOREST UNIVERSITY $8,342 Trans-NIH Recovery Act Research Support This research seeks to determine the role that extracellular matrix (ECM) plays in the aging of skeletal muscle. Skeletal muscle tissue is maintained via the regenerative capacity of the tissue's resident stem/progenitor cells known as satellite cells or National Institutes of Health 5/21/2009
WAKE FOREST UNIVERSITY $7,400 Trans-NIH Recovery Act Research Support The most important risk factor for the development of osteoarthritis (OA) is age but the mechanisms by which aging contributes to OA susceptibility are poorly understood. A key feature of OA is the progressive destruction and loss of articular cartilage r National Institutes of Health 8/05/2009
WAKE FOREST UNIVERSITY $6,216 Trans-NIH Recovery Act Research Support While trials such as the Diabetes Prevention Program have demonstrated a significant potential for the prevention of type 2 diabetes mellitus (DM) through lifestyle interventions, a critical knowledge gap is whether such approaches can be implemented in t National Institutes of Health 6/22/2009
WAKE FOREST UNIVERSITY $0 Trans-NIH Recovery Act Research Support This supplement is the NORDIC (Neuro-Ophthalmology Research Disease Investigator Consortium) Headquarters portion of a joint effort for both Drs Mark Kupersmith and Karl Kieburtz on behalf of our respective institutions, St. Luke?s Roosevelt Hospital and
This spending item is part of a $799,913 allocation. See details
National Institutes of Health 8/19/2009