Dollars for Profs

Dig Into University Researchers' Outside Income and Conflicts of Interest

Published Dec. 6, 2019

This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.

Financial doc
Filing Type

Conflict of Interest

Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.

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Carmela Abraham

Boston University Medical Campus, Department: Biochemistry

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Disclosed Conflict of Interest with

Klogene Therapeutics

Disclosed Value
Listed Reason
Payment for services (e.g., consulting fees, honoraria, paid authorship)

NA

Listed Research Project
Discovery of probes that enhance expression of the neuroprotective protein Klotho

Project Narrative Cognitive functions, such as learning and memory, are of fundamental biological importance, and diseases that affect these functions are among the most challenging biomedical problems of our time. We recently demonstrated that elevating levels of the pleotropic protein Klotho enhances cognitive functions in mice and humans, and can prevent synaptic and cognitive impairments in a transgenic mouse model that simulates key aspects of Alzheimer's disease. We hypothesize that small molecules capable of elevating Klotho levels (?Klotho boosters?) can prevent and reverse the pathogenic effects of elevated amyloid-? (A?) levels in the AD brain and therefore, in this proposal, we will begin to test these hypotheses by first identifying the best Klotho boosters for in vivo testing in wild type mice and for future testing in animal models of AD at the preclinical level.

Filed on January 24, 2017.

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Name Institution Type Company Disclosed Value
Carmela Abraham Boston University Medical Campus Conflict of Interest Klogene Therapeutics Value cannot be readily determined
Carmela Abraham Boston University Medical Campus Conflict of Interest Klogene Therapeutics Value cannot be readily determined
If you see an error in the database or a reason we should not disclose a record, please contact us at [email protected] and we'll evaluate it on a case-by-case basis.
Sources: National Institutes of Health, public records requests filed at multiple public state universities

Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.

Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.

ProPublica obtained additional financial disclosures and conflict of interest forms that we have not yet digitized and added to the database. You can download those disclosures in the ProPublica Data Store.

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