Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
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Joseph Italiano
Brigham and Women's Hospital, Department: Na
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Platelet Biogenesis
Equity Interest - Non-publicly traded entity ( e.g., stock, stock option, or other ownership interest)
Dr. Italiano has a financial interest in Platelet Biogenesis, a privately held company developing technologies related to generating platelets in a bioreactor. Dr. Italiano has an equity interest in this company, and is one of its founders. This research project focuses on the development and maturation of megakaryocytes, which are platelet cell precursors; if successful, the research could be added to the current Platelet Biogenesis technology and therefore increase its value. Based on the magnitude of Dr. Italiano’s financial interest in Platelet Biogenesis and the close connection between the company’s interests and the research, the review panel determined that the financial interest could directly and significantly affect the design, conduct, or reporting of the research.
Molecular mechanisms of megakaryocyte differentiation and maturation during inflammation
PROJECT NARRATIVE Platelets are essential to control bleeding and maintain hemostasis, and although more than 10 million platelet units are transfused yearly in the United States, the limited availability of donor platelets owing to their 5-day shelf life, potential to induce an immune response, and risk of bacterial contamination is of serious clinical concern. My preliminary data identify a mediator of platelet formation, the protein CCL5, which targets the development and maturation of platelet precursor cells, megakaryocytes. A better understanding of this protein and the mechanisms by which it regulates megakaryocyte differentiation, maturation, and platelet formation will lead to improved therapies for platelet disorders, and will therefore reduce morbidity and mortality in the United States.
Filed on November 18, 2016.
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Other search results for: “Joseph Italiano”
| Name | Institution | Type | Company | Disclosed Value |
|---|---|---|---|---|
| Joseph Italiano | Brigham and Women's Hospital | Conflict of Interest | Platelet BioGenesis | $0 - $4,999 |
| Joseph Italiano | Brigham and Women's Hospital | Conflict of Interest | Platelet Biogenesis | $0 - $4,999 |
| Joseph Italiano | Brigham and Women's Hospital | Conflict of Interest | Platelet BioGenesis | Value cannot be readily determined |
Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
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