Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
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Yang Shi
Children's Hospital Corporation, Department: Na
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Constellation Pharmaceuticals
Other : founder equity consult. income
Dr. Shi’s NIH funded research involves studying the histone demethylase, specifically in DNA damage response and the underlying molecular mechanisms. Constellation Pharmaceuticals aims to develop drugs targeting histone modifying enzymes and reader proteins to ultimately treat human diseases, with a focus on cancer. Although Dr. Shi’s research and the Company’s activity do not overlap, the outcome of the research may have the potential to indirectly benefit the company.
Histone demethylases and regulation of chromatin and transcription in eukaryotes
This application proposes to study the histone-modifying enzyme LSD1 in the DNA damage response pathway. Findings will significantly improve our understanding of how epigenetic regulators are involved in the regulation of genomic stability, which may impact the approaches used in epigenetic therapy.
Filed on November 12, 2013.
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Yang Shi filed other conflict of interest disclosures with the NIH:
| Name | Institution | Type | Company | Disclosed Value |
|---|---|---|---|---|
| Yang Shi | Boston Children's Hospital | Conflict of Interest | Constellation Pharmaceuticals, Inc. | >$600,000 |
| Yang Shi | Boston Children's Hospital | Conflict of Interest | Constellation Pharmaceuticals, Inc. | $0 - $4,999 |
Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
ProPublica obtained additional financial disclosures and conflict of interest forms that we have not yet digitized and added to the database. You can download those disclosures in the ProPublica Data Store.