Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
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Andrew Marks
Columbia University Health Sciences, Department: Physiology
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ARMGO Pharma Inc.
Payment for services (e.g., consulting fees, honoraria, paid authorship)
Dr. Marks owns equity in ARMGO Pharma Inc. and is a member of the company’s Board of Directors and chairman of the Scientific Advisory Board. In addition, ARMGO has licensed intellectual property from Columbia arising from Dr. Marks’ Columbia lab, and is engaged in drug development involving this technology. The company’s efforts may benefit from the outcome of the research under this grant. In light of these factors, Columbia has determined that the outcome of this research could affect the company and Dr. Marks’ financial interests in ARMGO, and that the design, conduct, and/or reporting of this research could be affected by Dr. Marks’ interests in ARMGO.
Molecular Basis of Heart Failure
Under conditions of stress including heart failure and muscular dystrophy ryanodine receptor/calcium release channels become 'leaky'. This intracellular calcium leak can drive heart failure progressive, trigger fatal cardiac arrhythmias, and promote muscle damage and decrease exercise capacity in muscular dystrophy animal models. A novel class of drugs called 'rycals' target the RyR mediated intracellular calcium leak and slow heart failure progression, prevent cardiac arrhythmias, and improve exercise capacity in animal models. A rycal is now in Phase II clinical trials for heart failure and cardiac arrhythmias. Thus, gaining new understandings of how the RyR/calcium release channels are regulated has important implications for developing novel therapies for heart and muscle diseases.
Filed on September 09, 2013.
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Andrew Marks filed other conflict of interest disclosures with the NIH:
| Name | Institution | Type | Company | Disclosed Value |
|---|---|---|---|---|
| Andrew Marks | Indiana Univ Purdue Univ at Indianapolis | Conflict of Interest | ARMGO Pharma Inc | $250,000 - $299,999 |
| Andrew Marks | Columbia University Health Sciences | Conflict of Interest | ARMGO | $250,000 - $299,999 |
| Andrew Marks | Columbia University Health Sciences | Conflict of Interest | ARMGO | $250,000 - $299,999 |
| Andrew Marks | Columbia University Health Sciences | Conflict of Interest | ARMGO Pharma Inc. | $0 - $4,999 |
| Andrew Marks | Columbia University Health Sciences | Conflict of Interest | ARMGO Pharma | Value cannot be readily determined |
| Andrew Marks | Indiana Univ Purdue Univ at Indianapolis | Conflict of Interest | ARMGO Pharma Inc | Value cannot be readily determined |
| Andrew Marks | Columbia University Health Sciences | Conflict of Interest | ARMGO Pharma | Value cannot be readily determined |
| Andrew Marks | Columbia University Health Sciences | Conflict of Interest | ARMGO Pharma | Value cannot be readily determined |
| Andrew Marks | Columbia University Health Sciences | Conflict of Interest | ARMGO Pharma Inc. | Value cannot be readily determined |
| Andrew Marks | Columbia University Health Sciences | Conflict of Interest | ARMGO | Value cannot be readily determined |
| Andrew Marks | Columbia University Health Sciences | Conflict of Interest | ARMGO Pharma | Value cannot be readily determined |
| Andrew Marks | Columbia University Health Sciences | Conflict of Interest | ARMGO | Value cannot be readily determined |
Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
ProPublica obtained additional financial disclosures and conflict of interest forms that we have not yet digitized and added to the database. You can download those disclosures in the ProPublica Data Store.