Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
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David Weinstock
Dana Farber Cancer Inst, Department: Na
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Travera, LLC
Equity Interest - Non-publicly traded entity ( e.g., stock, stock option, or other ownership interest)
see attachment
Overcoming resistance in BCR-ABL-rearranged acute lymphoblastic leukemia
Project Narrative B-cell acute lymphoblastic leukemia driven by the BCR-ABL fusion gene (BCR-ABL+ ALL) is the most common genetic subtype of ALL in adults but has historically had a poor prognosis, because even after initially responding to drugs targeting BCR-ABL, virtually all patients relapse, usually due to mutations in BCR-ABL that confer resistance to available drugs. We hypothesize that we can overcome this resistance in certain patients by combining existing BCR-ABL inhibitors with a new drug that binds BCR-ABL at a unique location and inhibits its activity by a distinct mechanism compared to currently available drugs. The goal of this project is to determine whether such combination therapy can cure animal models of BCR-ABL+ ALL and, in cases where it cannot, to use these animals to systematically define mechanisms of resistance, in order to guide the development of the next generation of treatments for this aggressive leukemia.
Filed on August 03, 2017.
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Other search results for: “David Weinstock”
| Name | Institution | Type | Company | Disclosed Value |
|---|---|---|---|---|
| David Weinstock | Massachusetts Institute of Technology | Conflict of Interest | Travera, LLC | Value cannot be readily determined |
| David Weinstock | Massachusetts Institute of Technology | Conflict of Interest | Travera, LLC | Value cannot be readily determined |
Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
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