Dollars for Profs

Dig Into University Researchers' Outside Income and Conflicts of Interest

Published Dec. 6, 2019

This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.

Financial doc
Filing Type

Conflict of Interest

Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.

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Richard Young

Dana Farber Cancer Inst, Department: Na

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Disclosed Conflict of Interest with

Syros Pharmaceuticals

Disclosed Value
Listed Reason
Equity Interest - Publicly traded entity (e.g., stock, stock option, or other ownership interest)

Dr. Young is a founder, member of the Board of Directors and consultant to Syros Pharmaceuticals. (The "payment for services" reported above includes compensation for consulting and Board service.) The interests of the company overlap with the research subject matter of the funded awards referenced above. A management plan is required to assure that Dr. Young's relationship with the companies will not influence the integrity of the research.

Listed Research Project
Transcriptional CDKs as therapeutic targets in MYC-dependent cancers

The potent oncogene MYCN is amplified in half of high-risk neuroblastoma cases, but devising strategies to inhibit this transcription factor has been challenging. We propose to take advantage of recent findings that oncogenic MYC upregulates the active transcriptional program in cancer cells and is transcriptionally regulated by large enhancer regions that facilitate its high-level expression and that are especially sensitive to perturbation. By using a novel covalent inhibitor of CDK7, a kinase that has crucial roles in gene transcription and cell cycle regulation, we will explore the potential of targeting MYCN-induced transcription as a novel therapeutic strategy for patients with MYCN-amplified neuroblastoma.

Filed on December 11, 2017.

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Name Institution Type Company Disclosed Value
Richard Young Whitehead Institute for Biomedical Res Conflict of Interest Syros Pharmaceuticals, Inc. $100,000 - $149,999
Richard Young Whitehead Institute for Biomedical Res Conflict of Interest Syros Pharmaceuticals, Inc. $100,000 - $149,999
Richard Young Massachusetts Institute of Technology Conflict of Interest Syros Pharmaceuticals Value cannot be readily determined
Richard Young Dana Farber Cancer Inst Conflict of Interest Syros Pharmaceuticals >$600,000
Richard Young Whitehead Institute for Biomedical Res Conflict of Interest Omega Therapeutics $20,000 - $39,999
Richard Young Whitehead Institute for Biomedical Res Conflict of Interest Syros Pharmaceuticals, Inc. $100,000 - $149,999
Richard Young Whitehead Institute for Biomedical Res Conflict of Interest Syros Pharmaceuticals, Inc. Value cannot be readily determined
Richard Young Whitehead Institute for Biomedical Res Conflict of Interest Marauder Therapeutics, Inc. $100,000 - $149,999
Richard Young Whitehead Institute for Biomedical Res Conflict of Interest Syros Pharmaceuticals, Inc. Value cannot be readily determined
If you see an error in the database or a reason we should not disclose a record, please contact us at [email protected] and we'll evaluate it on a case-by-case basis.
Sources: National Institutes of Health, public records requests filed at multiple public state universities

Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.

Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.

ProPublica obtained additional financial disclosures and conflict of interest forms that we have not yet digitized and added to the database. You can download those disclosures in the ProPublica Data Store.

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