Dollars for Profs

Dig Into University Researchers' Outside Income and Conflicts of Interest

Published Dec. 6, 2019

This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.

Financial doc
Filing Type

Conflict of Interest

Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.

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Scott Armstrong

Dana Farber Cancer Inst, Department: Na

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Disclosed Conflict of Interest with

C4 Therapeutics

Disclosed Value
Listed Reason
Equity Interest - Non-publicly traded entity ( e.g., stock, stock option, or other ownership interest)

NA

Listed Research Project
Targeting DOT1L for Degradation in MLL-rearranged Leukemia

Project Narrative Despite recent progress in our understanding of MLL-rearranged (MLL-r) leukemias, the disease remains difficult to cure, establishing an area of significant unmet medical need. While the first targeted therapies against DOT1L, an enzyme important for survival of MLL-r leukemia, have been realized in human clinical trials, early evidence suggests that resistance to these inhibitors has emerged. In this study, we will seek to define the biological foundation for acquired resistance to DOT1L therapy and overcome resistance through the development and optimization of a new class of small molecules that can degrade DOT1L protein, thus developing the tools and fundamental preclinical knowledge to help overcome this devastating disease.

Filed on September 12, 2018.

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Name Institution Type Company Disclosed Value
Scott Armstrong Dana Farber Cancer Inst Conflict of Interest C4 Therapeutics $20,000 - $39,999
Scott Armstrong Dana Farber Cancer Inst Conflict of Interest Epizyme, Inc. $5,000 - $9,999
Scott Armstrong Dana Farber Cancer Inst Conflict of Interest Epizyme, Inc. $0 - $4,999
If you see an error in the database or a reason we should not disclose a record, please contact us at [email protected] and we'll evaluate it on a case-by-case basis.
Sources: National Institutes of Health, public records requests filed at multiple public state universities

Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.

Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.

ProPublica obtained additional financial disclosures and conflict of interest forms that we have not yet digitized and added to the database. You can download those disclosures in the ProPublica Data Store.

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