Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
Should you be removed from our database? Contact us at [email protected]. Read more below.
Jian-Ting Zhang
Indiana Univ Purdue Univ at Indianapolis, Department: Pharmacology
Should you be removed from our database? Contact us at [email protected]. Read more below.
QRKanswer, LLC
Equity Interest - Non-publicly traded entity ( e.g., stock, stock option, or other ownership interest)
Investigator holds an equity interest in QRKanswer, LLC, whose goal is to develop next generation anticancer drugs based on Investigator’s discovery of a novel STAT3 inhibitor. QRKanswer, LLC also holds patent options related to Survivn inhibitors which is the research aim of this NIH award.
Effective targeting survivin dimerization interface with small molecule inhibitors
Project Narrative Due to lack of enzymatic activities, many ideal targets such as the homo-dimeric protein, survivin, are considered ?undruggable? and are avoided as target in drug discovery. Recently, we developed a novel concept and an automated computational method that allow us to identify a validated hit, LQZ-7, and several active analogues, which can inhibit survivin by disrupting homo- dimerization. In this application, we will further modify and optimize these compounds to develop potential new in-vivo chemical probes and drugs that directly work on and inhibit survivin for disease management.
Filed on October 16, 2018.
Tell us what you know about Jian-Ting Zhang's disclosure
We're still reporting about conflicts of interest. Is there something you'd like to tell us about this disclosure?
Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
ProPublica obtained additional financial disclosures and conflict of interest forms that we have not yet digitized and added to the database. You can download those disclosures in the ProPublica Data Store.