Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
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Anumantha Kanthasamy
Iowa State University, Department: Veterinary Sciences
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PK Biosciences Corporation
Equity Interest - Non-publicly traded entity ( e.g., stock, stock option, or other ownership interest)
PK Biosciences Corp. conducts research and development of therapeutic and diagnostic strategies for neurological diseases and the hypothesis for NIH-funded project entitled, "Mechanisms of Manganese Neurotoxicity" is that "Mn exposure transcriptionally upregulates proapoptotic PKCĪ“ gene to promote the neurotoxic response in the CNS." The FCOI determination is based on a determination that PK Biosciences Corp. could be perceived as benefiting from the NIH project.
Mechanisms of Manganese Neurotoxicity
Environmental exposure to excessive manganese impairs basal ganglia function, resulting in a neurological disorder relatively similar to Parkinsonism commonly known as Manganism. Manganese exposure is of serious concern due to the increased incidences of extrapyramidal neurological symptoms among miners and industrial workers, including welders. Manganese predominantly accumulates in the basal ganglia structures and causes mitochondrial dysfunction, oxidative stress, and apoptosis. However, cellular and molecular mechanisms underlying manganese neurotoxicity are poorly understood. The proposed study will elucidate the neurotoxic mechanisms underlying manganese induced upregulation of a proapoptotic kinase PKCd and its functional relevance to manganese neurotoxicity.
Filed on April 16, 2013.
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Anumantha Kanthasamy filed other conflict of interest disclosures with the NIH:
| Name | Institution | Type | Company | Disclosed Value |
|---|---|---|---|---|
| Anumantha Kanthasamy | Iowa State University | Conflict of Interest | PK Biosciences Corp. | Value cannot be readily determined |
| Anumantha Kanthasamy | Iowa State University | Conflict of Interest | PK Biosciences Corp | Value cannot be readily determined |
| Anumantha Kanthasamy | Iowa State University | Conflict of Interest | PK Biosciences Corporation | Value cannot be readily determined |
| Anumantha Kanthasamy | Iowa State University | Conflict of Interest | PK Biosciences Corporation | Value cannot be readily determined |
Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
ProPublica obtained additional financial disclosures and conflict of interest forms that we have not yet digitized and added to the database. You can download those disclosures in the ProPublica Data Store.