Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
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Benjamin Wolozin
Mayo Clinic Jacksonville, Department: Na
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Aquinnah Pharmaceuticals
Equity Interest - Non-publicly traded entity ( e.g., stock, stock option, or other ownership interest)
Please see attached.
The role of acetylation in regulating pathophysiology of tau
We seek to understand how the enzyme histone deacetylase 6 (HDAC6) and stress granules, which are protein/RNA complexes, drive disease progression in dementia. We aim to therapeutically tamp down HDAC6 to modulate two competing cellular processes, acetylation and phosphorylation, at specific cellular sites on the tau protein, thereby decreasing the harmful aggregation of tau and the neuronal response to stress. We will test whether treatment with antisense oligonucleotides (ASOs) diminishes disease progression in cell models and preserves cognition in mouse models, thereby providing key insights into the pre-clinical efficacy of HDAC6 ASOs as a novel therapeutic strategy.
Filed on September 18, 2014.
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Benjamin Wolozin filed other conflict of interest disclosures with the NIH:
| Name | Institution | Type | Company | Disclosed Value |
|---|---|---|---|---|
| Benjamin Wolozin | Boston University Medical Campus | Conflict of Interest | Aquinnah Pharmaceuticals | Value cannot be readily determined |
Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
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