Dollars for Profs

Dig Into University Researchers' Outside Income and Conflicts of Interest

Published Dec. 6, 2019

This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.

Financial doc
Filing Type

Conflict of Interest

Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.

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Horng Chen

Mayo Clinic Rochester, Department: Na

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Disclosed Conflict of Interest with

Zumbro Discovery, Inc.

Disclosed Value
Listed Reason
Other : Total IP royalties, through Mayo Clinic

Please see attached.

Listed Research Project
Novel Peptide Therapeutics for Hypertension

PROJECT NARRATIVE We propose to advance novel therapeutic designer peptides engineered by the applicants that targets the natriuretic peptide/pGC receptor-A/cGMP system for the treatment of resistant hypertension (RH). We will test MANP in African Americans who are at increased risk for RH and adverse cardiorenal outcomes. We also will define the cardiorenal and RAAS suppressing actions of a second-generation peptide called MANP2 in experimental hypertension. Finally, we will establish for the first time the ability to optimize this pathway by combining MANP2 and novel small molecule positive allosteric modulators representing an innovative synergism between a small molecule and therapeutic peptide.

Filed on May 15, 2019.

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Name Institution Type Company Disclosed Value
Horng Chen Mayo Clinic Rochester Conflict of Interest Zumbro Discovery, Inc. Value cannot be readily determined
Horng Chen Mayo Clinic Rochester Conflict of Interest Zumbro Discovery Value cannot be readily determined
If you see an error in the database or a reason we should not disclose a record, please contact us at [email protected] and we'll evaluate it on a case-by-case basis.
Sources: National Institutes of Health, public records requests filed at multiple public state universities

Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.

Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.

ProPublica obtained additional financial disclosures and conflict of interest forms that we have not yet digitized and added to the database. You can download those disclosures in the ProPublica Data Store.

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