Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
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Mark Federspiel
Mayo Clinic Rochester, Department: Na
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Omnis Pharma
Other : Intellectual property royalties through Mayo Clinic
Please see attached.
Intravenous Administration of Vesicular Stomatitis Vectors
Oncolytic virotherapy using live attenuated Vesicular Stomatitis Virus (VSV) is a promising new approach for the treatment of cancer. Intravenous administration of VSV resulted in one-shot cure of established myeloma in immunocompetent mice. However, when increasingly high doses of virus were given, there were unexpected toxicities in the form of abnormal liver function tests and metabolic parameters. We suspect that these toxicities are due to interaction of viral particles with host cells. In preparation for our application to the US FDA for systemic use of VSV in cancer patients, we are proposing a thorough investigation to identify the safe starting dose in multiple animal species as well as develop strategies to ameliorate toxicities associated with high dose IV VSV delivery.
Filed on August 28, 2015.
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Other search results for: “Mark Federspiel”
| Name | Institution | Type | Company | Disclosed Value |
|---|---|---|---|---|
| Mark Federspiel | Mayo Clinic Arizona | Conflict of Interest | Omnis Pharmaceutical | Value cannot be readily determined |
| Mark Federspiel | Mayo Clinic Rochester | Conflict of Interest | Omnis Pharma | Value cannot be readily determined |
| Mark Federspiel | Mayo Clinic Arizona | Conflict of Interest | Vyriad, Inc. | Value cannot be readily determined |
Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
ProPublica obtained additional financial disclosures and conflict of interest forms that we have not yet digitized and added to the database. You can download those disclosures in the ProPublica Data Store.