Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
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Ye Hu
Methodist Hospital Research Institute, Department: Na
Should you be removed from our database? Contact us at [email protected]. Read more below.
NanoVation Systems LLC
Intellectual property rights (e.g., royalties, patents, copyrights) not from the awardee Institution
The SFI, Dr Hu's invention, pending patent application USSB 61/732,266 (OTT201224 ESAT-6 Novel strategy for detection and measurement of human biologic fluid from nanoporous silica chips) is the diagnostic device that is the subject of the research. At the time of grant submission, the COI committee had determined that this SFI did not reach the threshold of a FCOI as there was no near term finanical interest or likelihood of commercialization. On February 19, 2015, Houston Methodist approved a proposed License agreement with NanoVation LLC. The final License agreement is anticipated in the near future. The Committee voted that this is a FCOI and has required a management plan.
Real-time Detection of Active TB in HIV Exposed Children on Customized Nanotrap
The current tuberculosis diagnostic methods are based on time-consuming bacterial isolation, culture, and identification (or by detection of bacterial DNA), which are especially difficult for childhood TB diagnosis due to the paucibacillary nature of the disease and difficulties in obtaining clinically relevant specimens. In this grant application we wll implement a quantitative biomarker detection and monitoring platform that combines a sophisticated peptide-enriching nanotechnology procedure ( Nanotrap ), with the powerful capabilities of bench-top mass spectrometry (MS), without the use of complicated bacterial isolation procedures or antibodies to address the challenge in the field of active TB detection and control in HIV exposed children. Our ultimate goal for this study is to use the Nanotrap-MS for early identification of TB infection in this vulnerable patient population and to assess TB biomarker fluctuations as a function of anti-TB therapies; and we are confident that this to be a high-impact strategy that could decrease the likelihood of transmission, improve therapeutic regimens, and prevent the emergence of drug resistance TB strains.
Filed on March 10, 2015.
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Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
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