Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
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Chad Mirkin
Northwestern University at Chicago, Department: Neurology
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Exicure
Equity Interest - Non-publicly traded entity ( e.g., stock, stock option, or other ownership interest)
This research uses novel RNAi-based nanoconjugates, termed Spherical Nucleic Acids (SNAs) to neutralize Bcl2L12 expression in established glioma; the foundational SNA intellectual property is licensed to Exicure, an entity in which the investigator has significant financial interests, as well as AuraSense, which is the parent company holding the intellectual property interests. Continued development and application of these SNAs through this research results in a perceived conflict of interest that should be managed.
Systemic RNA interference to reactivate p53 tumor suppression
In this proposal, we will molecularly characterize and therapeutically evaluate a multi-modal regimen to restore p53 activation in solid cancers, in particular glioblastoma, using RNAi-based nanotechnological conjugates targeted to the p53 inhibitor Bcl2L12. The goal is to overcome the notorious resistance of solid tumors to chemotherapy, and implement p53 reactivation as a broadly applicable anti-neoplastic strategy.
Filed on March 16, 2017.
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Other search results for: “Chad Mirkin”
| Name | Institution | Type | Company | Disclosed Value |
|---|---|---|---|---|
| Chad Mirkin | Northwestern University at Chicago | Conflict of Interest | Exicure | $100,000 - $149,999 |
| Chad Mirkin | Northwestern University at Chicago | Conflict of Interest | AuraSense Therapeutics, LLC | $5,000 - $9,999 |
| Chad Mirkin | Northwestern University at Chicago | Conflict of Interest | Exicure | $100,000 - $149,999 |
| Chad Mirkin | Northwestern University at Chicago | Conflict of Interest | Exicure | Value cannot be readily determined |
| Chad Mirkin | Northwestern University at Chicago | Conflict of Interest | Exicure | $100,000 - $149,999 |
| Chad Mirkin | Northwestern University at Chicago | Conflict of Interest | Exicure, Inc. | Value cannot be readily determined |
| Chad Mirkin | Northwestern University at Chicago | Conflict of Interest | AuraSense, LLC | Value cannot be readily determined |
| Chad Mirkin | Northwestern University | Conflict of Interest | AuraSense Therapeutics, LLC | $5,000 - $9,999 |
| Chad Mirkin | Northwestern University | Conflict of Interest | AuraSense Therapeutics, LLC | Value cannot be readily determined |
| Chad Mirkin | Northwestern University at Chicago | Conflict of Interest | AuraSense | Value cannot be readily determined |
Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
ProPublica obtained additional financial disclosures and conflict of interest forms that we have not yet digitized and added to the database. You can download those disclosures in the ProPublica Data Store.