Dollars for Profs

Dig Into University Researchers' Outside Income and Conflicts of Interest

Published Dec. 6, 2019

This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.

Financial doc
Filing Type

Conflict of Interest

Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.

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Luca Inverardi

Ophysio, Inc., Department: Na

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Disclosed Conflict of Interest with

Ophysio, Inc.

Disclosed Value
Listed Reason
Equity Interest - Non-publicly traded entity ( e.g., stock, stock option, or other ownership interest)

Dr. Inverardi holds (b)(4) equity in Ophysio. Ophysio is a start-up company whose value cannot be readily determined through reference to public prices or other reasonable measures of fair market value.
Dr. Inverardi is an inventor of intellectual property (IP) used in the PHS-funded research. The IP is licensed to Ophysio, in which Dr. Inverardi has the aforementioned financial interest.

Listed Research Project
technologyIn vitro maturation of BMP-7-responsive pancraeatic beta cell progenitors by oxygen modulation

NARRATIVE Progress in the efficient generation of insulin-producing cells is expected to result in new cell therapies for type 1 and 2 diabetes (T1/2D). Ophysio, Inc. has successfully developed a platform to aid in the differentiation of such cells from different sources. Our patented technology is based on the accurate provision of physiological oxygenation, which conventional means of culture cannot achieve. Here we seek to expand the application of this principle to the maturation of a novel sub-population of pancreatic progenitor cells that our collaborators at the University of Miami have described in human non-endocrine pancreatic tissue (hNEPT), which comprises 98% of the pancreas and is routinely discarded after the insulin-producing islets (used for islet transplantation) are isolated. These progenitors are characterized by their responsiveness to BMP-7, an FDA-approved agent. Coupled with Ophysio?s technology for enhanced maturation, this approach has rapid translational potential for the effective treatment of T1/2D, and as such is highly aligned with the NIH mission.

Filed on November 22, 2016.

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Name Institution Type Company Disclosed Value
Luca Inverardi Ophysio, Inc. Conflict of Interest Ophysio, Inc. Value cannot be readily determined
If you see an error in the database or a reason we should not disclose a record, please contact us at [email protected] and we'll evaluate it on a case-by-case basis.
Sources: National Institutes of Health, public records requests filed at multiple public state universities

Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.

Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.

ProPublica obtained additional financial disclosures and conflict of interest forms that we have not yet digitized and added to the database. You can download those disclosures in the ProPublica Data Store.

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