Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
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Patricia Opresko
Pna Innovations, Inc., Department: Na
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University of Pittsburgh
Other : Intellectual property rights (e.g., royalties, patents, copyrights) assigned to the University of Pittsburgh.
Dr. Opresko’s conflict arises due to her interest as an inventor of intellectual property being developed in this bench research, which the University of Pittsburgh licensed to PNA Innovations.
GammaPNA Miniprobes for Telomere Analysis and RNA FISH
The goals of this project are to further develop a new class of fluorescent in situ hybridization (FISH) probes for telomere analysis and to extend this technology to RNA FISH applications. The technology is based on work done in two academic laboratories and is well suited to commercial development, as is the goal of PA-15-052, 'Lab to Marketplace: Tools for Biomedical and Behavioral Research'. The probes will be based on gammaPNA, an analogue of peptide nucleic acid that exhibits superior affinity and solubility. The higher affinity of gammaPNA allows shorter 'miniprobes' to be used. The ability to hybridize shorter probes means that more probes can hybridize to a given telomere, resulting in brighter fluorescence. This significantly improves the analysis of critically short telomeres, which are correlated with a variety of aging-related diseases, cancer and other conditions. New applications in this proposal include (1) development of a high-throughput telomere analysis assay, (2) testing of miniprobes for telomere analysis in fresh and archived tissue samples, and (3) generation of sets of probes for labeling non-repetitive targets such as mRNAs. The miniprobes will be synthesized at PNA Innovations Inc, then tested at Carnegie Mellon University and the University of Pittsburgh. Optimized miniprobes will then be delivered to beta testing laboratories for independent testing and feedback.
Filed on October 13, 2016.
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Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
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