Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
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Junichi Sadoshima
Rbhs New Jersey Medical School, Department: Anatomy/cell Biology
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Rutgers, The State University of New Jersy
Other : Intellectual Property Rights owned by the University
Dr. Sadoshima has a patent entitled, ‘MST 1 Modulation of Apoptosis in Cardiac Tissue and Modulators of MST1 Treatment and Prevention of Cardiac Disease”, US patent number 007160859B2 dated 1/9/2007, held by Rutger, The State University of NJ. This is an NIH funded grant and under the major goals of the project it is stated that….”We will investigate where MST1 is activated in cells and where MST1 phosphorylates its downstream targets…..” The grant will also focus on the RASSf1-MST1 and MST1-Lats pathways. The Committee agreed that this has clear relatedness to the subject of the patent. Dr. Sadoshima will generate and interpret the data and publish the results. Hence, he is in a position to bias the data in favor of the patent, increasing the likelihood of licensing it and enhancing his financial interests. After discussion, the Rutgers Conflict of Interest Committee concluded that Dr. Sadoshima’s role in the holding of the MST1 patent does represent a conflict of interest (COI) in this case.
REGULATION OF MYOCARDIAL GROWTH AND DEATH BY THE HIPPO PATHWAY
Project Narrative We will investigate why the Hippo signaling pathway, known to promote death of cardiomyocytes, exists in the heart. Our hypothesis is that the activity of the Hippo pathway is required for the heart cells to maintain a well-organized structure and to generate contractile force against blood pressure. Disruption of this mechanism may be responsible for the cardiac dysfunction observed in some forms of cardiomyopathy.
Filed on February 14, 2018.
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Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
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