Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
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David Scheinberg
Sloan Kettering Inst Can Research, Department: Na
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Eureka Therapeutics
Equity Interest - Non-publicly traded entity ( e.g., stock, stock option, or other ownership interest)
Eureka Therapeutics is a joint-owner with Memorial Sloan Kettering Cancer Center of the “antibodies recognizing/binding WT-1 petide/HLA-A-2”. Dr. Scheinberg has a consulting agreement with Eureka and the compensation for those services is equity.
Mechanisms of action of a TCR-like antibody to WT1
Human mAb therapies alone, as cytotoxic conjugates, or in combination with other agents, have proven to be potent, controllable and highly effective treatment modalities for several cancers and leukemias. However, marketed therapeutic anti-cancer antibodies recognize extracellular or cell surface proteins, which constitute only a small fraction of the cellular proteins and are not generally tumor specific. In contrast, the mutated proteins that cause cancer are typically hidden inside the cell. Here, propose an antibody that can attack these proteins in many cancers. We also propose to develop an animal model to accurately test the mechanism by which the antibody kills the cancer cells before human uses.
Filed on November 20, 2018.
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David Scheinberg filed other conflict of interest disclosures with the NIH:
| Name | Institution | Type | Company | Disclosed Value |
|---|---|---|---|---|
| David Scheinberg | Sloan Kettering Inst Can Research | Conflict of Interest | Novartis | $400,000 - $449,999 |
Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
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