Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
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Timothy Chan
Sloan Kettering Inst Can Research, Department: Na
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Personal Genome Diagnostics
Intellectual property rights (e.g., royalties, patents, copyrights) not from the awardee Institution
Dr. Chan is co-inventor of intellectual property related to tumor mutation burden for prediction of immunotherapy response; MSK has licensed this technology to Personal Genome Diagnostics (PGDx). This project proposes to investigate how tumor and patient genetics/genomics affect tumor immune phenotypes and influence the response and resistance to immunotherapies.The aims of this research intersect with Personal Genome Diagnostics' focus on diagnostic technology to measure tumor mutation burden in order to predict response to immunotherapy.
Towards Precision Immuno-Oncology: Unraveling the Genomic Determinants and Mechanisms Underlying Immunotherapy Efficacy and Resistance
PROJECT NARRATIVE This proposal focuses on elucidating the genetic determinants and mechanisms underlying immune checkpoint blockade therapy efficacy and resistance. We propose to use a combination of systematic large-scale genomics, preclinical animal modeling, integrated immunogenomics profiling, and mechanism-directed immunologic analyses to establish a robust understanding of sensitivity and resistance to immune checkpoint blockade. Our studies will build the foundation for the precise and individual application on immunotherapy for cancer patients.
Filed on June 26, 2019.
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Timothy Chan filed other conflict of interest disclosures with the NIH:
| Name | Institution | Type | Company | Disclosed Value |
|---|---|---|---|---|
| Timothy Chan | Sloan Kettering Inst Can Research | Conflict of Interest | Gritstone Oncology | $350,000 - $399,999 |
| Timothy Chan | Sloan Kettering Inst Can Research | Conflict of Interest | Gritstone Oncology | $350,000 - $399,999 |
Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
ProPublica obtained additional financial disclosures and conflict of interest forms that we have not yet digitized and added to the database. You can download those disclosures in the ProPublica Data Store.