Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
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Karl Kelsey
Tufts University Boston, Department: Public Health & Prev Medicine
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Celintec
Equity Interest - Non-publicly traded entity ( e.g., stock, stock option, or other ownership interest)
Brown’s Conflict of Interest Review Board reviewed Dr. Kelsey’s SFI in Celintec in connection with the R01 grant referenced above. Celintec a privately held start-up company that was founded in an effort to commercialize a method, developed by Brown, to utilize DNA methylation signatures to infer immune profiles from peripheral blood. The chief IP relates to the software to deconvolute DNA methylation data to cell subtype. Potential uses include immune monitoring for clinical trials, or targeted clinical applications where conventional immune profiling with flow cytometry is difficult or impossible. The company is attempting to commercialize methods that identify biomarkers of immune response primarily in cancer.
The COI Review Board determined that Dr. Kelsey’s SFI is related to the research proposed under the R01 grant. The award is similar, in that it has the goal of developing methylation marks of specific cell types that predict response to treatment and outcome. As better immune biomarkers are developed, they could be commercialized by Celintec. Given the type and level of his SFI, the COI Board further determined that Dr. Kelsey’s SFI could directly and significantly affect the design, conduct, or reporting of the research; that is, his SFI creates an FCOI requiring management.
Prospective immune profiling using methylation markers and pancreatic cancer risk
PROJECT NARRATIVE Pancreatic cancer is the fourth leading cause of cancer-related death in the US and is the most rapidly fatal cancer. Early detection is critical for improving prognosis and survival from this disease given that treatment is purely palliative for patients diagnosed late in the progression of the disease. Studies, including ours, suggest that the immune response plays an important role in carcinogenesis; in this proposal, we propose to use DNA methylation markers to identify immune profiles predictive of pancreatic cancer risk.
Filed on December 11, 2018.
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Other search results for: “Karl Kelsey”
| Name | Institution | Type | Company | Disclosed Value |
|---|---|---|---|---|
| Karl Kelsey | University of California, San Francisco | Conflict of Interest | Cellintec | $0 - $4,999 |
| Karl Kelsey | Dartmouth College | Conflict of Interest | Celintec | Value cannot be readily determined |
| Karl Kelsey | Columbia University Health Sciences | Conflict of Interest | Celintec | Value cannot be readily determined |
Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
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