Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
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Nora D. Mineva
Tufts University Boston, Department: Biochemistry
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Adecto Pharmaceuticals
Other : Co- founder, on the board of directors and Chief Scientific Officer
NA
ADAM8 Is a Novel Target for Treatment of Triple-Negative Breast Cancer
Triple-Negative Breast Cancer (TNBC) represents only 15% of breast tumor cases but is highly metastatic, and accounts for more than 25% of the 500,000 breast cancer deaths yearly worldwide. There is an urgent need for new treatment regimens for TNBC as current options are restricted to chemotherapy and radiation, which are insufficient to block tumor progression, relapse or metastatic dissemination, and have severe side effects. Here we propose preclinical studies to validate a novel antibody-based therapy targeting two extracellular domains of a transmembrane protein called ADAM8, which if confirmed could revolutionize treatment modalities for patients with ADAM8-expressing TNBC by providing safe, effective interventions that reduce growth and metastases of these very aggressive tumors.
Filed on August 23, 2017.
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Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
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