Dollars for Profs

Dig Into University Researchers' Outside Income and Conflicts of Interest

Published Dec. 6, 2019

This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.

Filing Type

Conflict of Interest

Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.

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Hong-Yu Li

Univ of Arkansas for Med Scis, Department: Pharmacology

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Disclosed Conflict of Interest with

Synactix Pharmaceuticals, Inc.

Disclosed Value

Value cannot be readily determined

Listed Reason

Intellectual property rights (e.g., royalties, patents, copyrights) not from the awardee Institution

The Investigator has a proprietary interest that is licensed to Synactix Pharmaceuticals as well as an equity interest in Synactix Pharmaceuticals, and performs research that the potential to affect the value of these interests.

Listed Research Project

Discovery and Development of a Selective pan-FLT3-ITD Kinase Inhibitor Clinical Candidate for the Treatment of FLT3-ITD-Driven AML

Pathological activating mutations in the FLT3 kinase represent the most common genetic alteration in patients with acute myeloid leukemia (AML), occurring in approximately one-third of all cases. In a research effort we will use x-ray crystal structure analysis, computational models, and fragment-based screening to develop an FLT3 inhibitor clinical candidate with broad activity on FLT3-ITD and secondary mutants. The resulting selective FLT3 inhibitor is expected to dramatically increase AML survival.

Filed on October 29, 2018.

Name	Institution	Type	Company	Disclosed Value
Hong-Yu Li	Univ of Arkansas for Med Scis	Conflict of Interest	Synactix Pharmaceuticals, Inc.	Value cannot be readily determined
Hong-Yu Li	Univ of Arkansas for Med Scis	Conflict of Interest	Synactix Pharmaceuticals, Inc.	Value cannot be readily determined
Hong-Yu Li	Univ of Arkansas for Med Scis	Conflict of Interest	Synactix Pharmaceuticals, Inc.	Value cannot be readily determined
Hong-Yu Li	Univ of Arkansas for Med Scis	Conflict of Interest	Synactix Pharmaceuticals, Inc.	Value cannot be readily determined
Hong-Yu Li	Univ of Arkansas for Med Scis	Conflict of Interest	Synactix Pharmaceuticals, Inc.	Value cannot be readily determined
Hong-Yu Li	Univ of Arkansas for Med Scis	Conflict of Interest	Synactix Pharmaceuticals, Inc.	Value cannot be readily determined
Hong-Yu Li	Univ of Arkansas for Med Scis	Conflict of Interest	Synactix Pharmaceuticals, Inc.	Value cannot be readily determined

If you see an error in the database or a reason we should not disclose a record, please contact us at [email protected] and we'll evaluate it on a case-by-case basis.

Sources: National Institutes of Health, public records requests filed at multiple public state universities

Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.

Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.

ProPublica obtained additional financial disclosures and conflict of interest forms that we have not yet digitized and added to the database. You can download those disclosures in the ProPublica Data Store.