Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
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Chengwen Li
Univ of North Carolina Chapel Hill, Department: Pediatrics
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Bedrock Therapeutics
Equity Interest - Non-publicly traded entity ( e.g., stock, stock option, or other ownership interest)
The SFIs of the investigator are related to the funded research since the technology being used in the project has been licensed to the company with which the investigator has multiple relationships.
The Institution has determined that since the technology could be further validated as a result of the research, these financial interests could conflict with project.
Optimization of AAV vector to deliver FVa for hemophilia with inhibitors
PROJECT NARRATIVE Adeno-associated virus (AAV) vector-mediated gene delivery has been successful in hemophilia patients. However, the patients with inhibitors are excluded from these trials. We have demonstrated that AAV delivery of activated factor V (FVa) improved hemostasis in hemophilic mice. We will explore optimization of FVa cassettes delivered by AAV vectors for phenotypic correction in hemophilia with inhibitors. This study will allow us to design safer and more effective strategies for hemophilia treatment using AAV.
Filed on March 13, 2019.
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Chengwen Li filed other conflict of interest disclosures with the NIH:
| Name | Institution | Type | Company | Disclosed Value |
|---|---|---|---|---|
| Chengwen Li | Univ of North Carolina Chapel Hill | Conflict of Interest | Bedrock Therapeutics | $0 - $4,999 |
Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
ProPublica obtained additional financial disclosures and conflict of interest forms that we have not yet digitized and added to the database. You can download those disclosures in the ProPublica Data Store.