Dollars for Profs

Dig Into University Researchers' Outside Income and Conflicts of Interest

Published Dec. 6, 2019

This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.

Financial doc
Filing Type

Conflict of Interest

Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.

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Jorge Barrio

University of California Los Angeles, Department: None

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Disclosed Conflict of Interest with

CTEM as TauMark

Disclosed Value
Listed Reason
Equity Interest - Non-publicly traded entity ( e.g., stock, stock option, or other ownership interest)

Professor Barrio is a Co-Investigator and will be responsible for [F-18]FDDNP and [C-11]PIB. He will work closely with Professor Small on design and methods of this project. He is a founder of the company.

From our review of the Management is unclear whether the human subjects and data analysis restrictions are a suggestion/recommendation or a requirement. We ask the University to please clarify, and if the restrictions are NOT a requirement, we believe the FCOI should be disclosed in the consent.

1. The data analysis restrictions are required.

2. The fact that Drs. Small and Barrio have personal financial interests in the TauMark is disclosed in the approved informed consent form.

Language from the Approved Informed Consent Form for the study:

Drs. Gary Small and Jorge Barrio have a personal financial interest in the company sponsoring this study CTEM (as TauMark). Specifically, Drs. Gary Small and Jorge Barrio are receiving salary/payment under CTEM (as TauMark) and are co-

inventors of Intellectual Property owned by the Regents, licensed to TauMark and being used as a research tool. A UCLA committee has reviewed these financial interests to help prevent them from affecting the quality and reliability of this study.”

Listed Research Project
Brain aging and treatment response in geriatric depression

The proposed project will evaluate the role of neuroimaging biomarkers of brain aging (i.e., neurodegenerative and vascular brain changes) and mild cognitive impairment in the patterns of treatment response to memantine combined with escitalopram compared to escitalopram and placebo. Memantine is likely to accelerate and enhance antidepressant response, to escitalopram and improve cognitive performance. Subjects with amnestic mild cognitive impairment or biomarkers of brain aging at baseline are likely to have preferential response to the combination of memantine and escitalopram compared to escitalopram and placebo, thus identifying a more personalized treatment approach in the high-risk subgroups for poor clinical outcomes.

Filed on February 24, 2015.

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Name Institution Type Company Disclosed Value
Jorge Barrio University of California Los Angeles Conflict of Interest CTEM as TauMark Value cannot be readily determined
If you see an error in the database or a reason we should not disclose a record, please contact us at [email protected] and we'll evaluate it on a case-by-case basis.
Sources: National Institutes of Health, public records requests filed at multiple public state universities

Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.

Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.

ProPublica obtained additional financial disclosures and conflict of interest forms that we have not yet digitized and added to the database. You can download those disclosures in the ProPublica Data Store.

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