Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
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Kevan Shokat
University of California, San Francisco, Department: Neurology
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Revolution Medicines
Equity Interest - Non-publicly traded entity ( e.g., stock, stock option, or other ownership interest)
NA
Improving the efficacy of mTOR inhibition
Project Narrative We describe a novel mTOR inhibitor, RapaLink-1, that is 1-2 logs more potent that existing mTOR inhibitors, is blood brain barrier permeable, accumulates in glioblastoma tumor cells and shows efficacy in-vivo. We propose a detailed characterization, including analysis of efficacy, identification of response biomarkers, and development and characterization of existing and novel agents that enhance efficacy in combination. Successful completion provides the preclinical rational to initiate a clinical trial of RapaLink-1 in patients with glioblastoma.
Filed on March 01, 2019.
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Kevan Shokat filed other conflict of interest disclosures with the NIH:
| Name | Institution | Type | Company | Disclosed Value |
|---|---|---|---|---|
| Kevan Shokat | University of California, San Francisco | Conflict of Interest | Revolution Medicines | $20,000 - $39,999 |
Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
ProPublica obtained additional financial disclosures and conflict of interest forms that we have not yet digitized and added to the database. You can download those disclosures in the ProPublica Data Store.