Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
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Alexander Ruthenburg
University of Chicago, Department: Genetics
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EpiCypher, Inc.
Equity Interest - Non-publicly traded entity ( e.g., stock, stock option, or other ownership interest)
Alexander Ruthenburg, PhD has equity interest in the privately-held company EpiCypher, Inc., a small epigenetics company. Equity was given as a form of payment for consulting and advisory services. The University has also licensed patented technology being applied in the grant,ICeChIP, for which Dr. Ruthenburg is named as inventor. Because IP licensed to a company in which the PI holds equity, the University has determined that a potential financial conflict of interest exists that must be managed in relation to this research.
Quantitatively probing intra-nucleosomal chromatin variation and function
Present technology permits only crude measurement of relative amounts of chromatin marks and histone variants at a given place in the genome or quantification of their global levels, but fine-grained detail about the arrangements and patterns of these marks in the fundamental repeating structure of chromatin is lacking. We have devised a new method to probe this largely unstudied level of chromatin structure and will use it to drive a more quantitative maps of the epigenetic landscape. These maps should provide fundamental insight into the epigenetic regulation of transcription and gene control in stem cells and their differentiation; follow-on experiments will probe the mechanisms by which these modification patterns act, as well as their biogenesis and functional importance.
Filed on April 29, 2019.
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Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
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