Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
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Wenbin Lin
University of Chicago, Department: Chemistry
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Coordination Pharmaceuticals
Equity Interest - Non-publicly traded entity ( e.g., stock, stock option, or other ownership interest)
Professor Lin is the founder of Coordination Pharmaceuticals. His intellectual property (NCPs) that is licensed to Coordination Pharmaceuticals will be
further developed and studied in the project, "Nanoscale Coordination Polymers Co-deliver Chemotherapeutics and siRNAs for Efficacious Treatment of Resistant
Ovarian Cancer". For this grant, he proposes to develop robust nanoscale coordination polymers (NCPs) for the
co-delivery of chemotherapeutic agents and small interfering RNA (siRNA) cocktails targeting multi-drug resistance pathways. NCPs
carrying chemotherapeutic agents and siRNAs targeting these genes will be designed as personalized therapies for treating patients with
resistant ovarian cancer.
Nanoscale Coordination Polymers Co-deliver Chemotherapeutics and siRNAs for Efficacious Treatment of Resistant Ovarian Cancer
Project Narrative Resistant ovarian cancers are a terminal disease that cannot be cured with existing therapeutics. We propose to develop robust nanoscale coordination polymers (NCPs) for the co-delivery of chemotherapeutic agents (cisplatin or cisplatin plus gemcitabine) and small interfering RNA (siRNA) cocktails targeting multi-drug resistance (MDR) pathways. By identifying three MDR genes with the highest expression levels in patients' tumors, NCPs carrying chemotherapeutic agents and siRNAs targeting these genes will be designed as personalized therapies for treating these patients with resistant OCa.
Filed on February 08, 2019.
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Wenbin Lin filed other conflict of interest disclosures with the NIH:
| Name | Institution | Type | Company | Disclosed Value |
|---|---|---|---|---|
| Wenbin Lin | University of Chicago | Conflict of Interest | Intellectual Property: Frameworks for light-triggered and Xray induced photodynamic therapy | Value cannot be readily determined |
| Wenbin Lin | University of Chicago | Conflict of Interest | Intellectual Property: Frameworks for light-triggered and Xray induced photodynamic therapy | Value cannot be readily determined |
| Wenbin Lin | University of Chicago | Conflict of Interest | Coordination Pharmaceuticals, Inc. | Value cannot be readily determined |
| Wenbin Lin | University of Chicago | Conflict of Interest | RiMO Therapeutics, LLC | Value cannot be readily determined |
| Wenbin Lin | University of Chicago | Conflict of Interest | RiMO Therapeutics, LLC | Value cannot be readily determined |
Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
ProPublica obtained additional financial disclosures and conflict of interest forms that we have not yet digitized and added to the database. You can download those disclosures in the ProPublica Data Store.