Dollars for Profs

Dig Into University Researchers' Outside Income and Conflicts of Interest

Published Dec. 6, 2019

This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.

Financial doc
Filing Type

Conflict of Interest

Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.

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Charles M. Brenner

University of Iowa, Department: Anesthesiology

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Disclosed Conflict of Interest with

ChromaDex, Inc.

Disclosed Value
Listed Reason
Equity Interest - Publicly traded entity (e.g., stock, stock option, or other ownership interest)

Since Dr. Brenner has equity in and receives payment for consulting from the company whose product is being evaluated, and receives royalties from the company for the product being evaluated, bias or influence could be introduced into the research. Based on this analysis, we have determined that the interests could directly and significantly affect the design, conduct, or reporting of the PHS-funded research, or have the appearance of doing so.

Listed Research Project
Mechanistic Studies of the Natural Product Nicotinamide Riboside for Relief of Painful Sensory Neuropathy

Painful peripheral neuropathies are difficult to treat and a significant health care problem, particularly in the case of chemotherapy-induced peripheral neuropathies (CIPN) for which there are no evidence-based treatments. The finding that the natural product nicotinamide riboside, a vitamin B3 precursor of NAD+ that can correct mitochondrial dysfunction, ameliorates CIPN but not sensory neuropathy produced by frank nerve injury provides a unique opportunity to rigorously test several hypotheses concerning the mechanism of CIPN and other neuropathies. The results may lead to a better understanding of the mechanisms of CIPN, development of the first effective treatment for CIPN, and insight into why nicotinamide riboside will not be a universal treatment for all types of painful sensory neuropathies.

Filed on April 02, 2018.

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Name Institution Type Company Disclosed Value
Charles M. Brenner University of Iowa Conflict of Interest ChromaDex, Inc. $20,000 - $39,999
Charles M. Brenner University of Iowa Conflict of Interest ChromaDex, Inc. $20,000 - $39,999
If you see an error in the database or a reason we should not disclose a record, please contact us at [email protected] and we'll evaluate it on a case-by-case basis.
Sources: National Institutes of Health, public records requests filed at multiple public state universities

Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.

Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.

ProPublica obtained additional financial disclosures and conflict of interest forms that we have not yet digitized and added to the database. You can download those disclosures in the ProPublica Data Store.

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