Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
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David Watt
University of Kentucky, Department: Radiation Diagnostic/oncology
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Curonc, LLC
Equity Interest - Non-publicly traded entity ( e.g., stock, stock option, or other ownership interest)
NA
Suppression of Prostate Tumor Growth and Metastasis by Inhibition of Vimentin
The proposed studies will examine the role of vimentin in intracellular sequestration of the tumor suppressor Par-4, and the ability of a novel small molecule 3-arylquinoline called Arylquin-1, which targets vimentin, in releasing Par-4 from vimentin for secretion and paracrine apoptosis of prostate cancer cells. Moreover, owing to its vimentin-targeting ability, Arylquin-1 will be also studied for inhibition of prostate cancer cell motility, invasion, EMT and tumor metastasis that are promoted by vimentin function. Both cell culture and mouse models of prostate cancer will be used to determine the effect of Arylquin-1 on Par-4 secretion, apoptosis, and inhibition of EMT and metastasis.
Filed on August 05, 2015.
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Other search results for: “David Watt”
| Name | Institution | Type | Company | Disclosed Value |
|---|---|---|---|---|
| David Watt | University of Kentucky | Conflict of Interest | Epionc, Inc. | Value cannot be readily determined |
| David Watt | University of Kentucky | Conflict of Interest | Liu-Watt, LLC | Value cannot be readily determined |
Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
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