Dollars for Profs

Dig Into University Researchers' Outside Income and Conflicts of Interest

Published Dec. 6, 2019

This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.

Financial doc
Filing Type

Conflict of Interest

Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.

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Bruce Freeman

University of Pittsburgh at Pittsburgh, Department: Pharmacology

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Disclosed Conflict of Interest with

Complexa, Inc.

Disclosed Value
Listed Reason
Other : IP rights to UPitt/UAB - licensed

Dr. Freeman’s conflict arises due to his interest as an inventor of the intellectual property being evaluated/developed in this human subject research, which the University of Pittsburgh and the University of Alabama, Birmingham licensed to Complexa. Dr. Freeman also has an ownership interest in the company.

Listed Research Project
The Effects of Nitrate/Nitrite and Conjugated Linoleic Acid Supplementation on the Obese Asthmatic Pathology

Project Narrative This project will determine the effects of nitrogen oxides (NOx, nitrate and nitrite) and conjugated linoleic acid (cLA) on airway hyperresponsiveness and systemic and airway-specific inflammation in obese asthmatics. These species have reported individual beneficial effects on cardiovascular function, inflammatory signaling, airway hyperresponsiveness and metabolic syndrome. In addition to their individual benefits, these species are the precursors of nitro-conjugated linoleic acid (NO2-cLA). NO2-cLA is an electrophilic nitro fatty acid with pleiotropic signaling properties and has been shown to abrogate inflammation. Obese asthmatics suffer from chronic, systemic inflammation that contributes to complications in lung function. In addition, increased body mass index is associated with nitric oxide synthase uncoupling leading to low nitric oxide bioavailability and increased formation of superoxide. This dietary supplement (NOx + cLA) approach will address obesity- derived and asthma-derived inflammation, increase nitric oxide bioavailability and reduce airway hyperresponsiveness.

Filed on July 14, 2016.

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Name Institution Type Company Disclosed Value
Bruce Freeman University of Pittsburgh at Pittsburgh Conflict of Interest Complexa, Inc. Value cannot be readily determined
Bruce Freeman University of Pittsburgh at Pittsburgh Conflict of Interest Complexa, Inc. Value cannot be readily determined
Bruce Freeman University of Pittsburgh at Pittsburgh Conflict of Interest Complexa, Inc. Value cannot be readily determined
Bruce Freeman University of Pittsburgh at Pittsburgh Conflict of Interest Complexa, Inc. Value cannot be readily determined
Bruce Freeman University of Pittsburgh at Pittsburgh Conflict of Interest Complexa, Inc. Value cannot be readily determined
Bruce Freeman University of Pittsburgh at Pittsburgh Conflict of Interest Complexa, Inc. Value cannot be readily determined
Bruce Freeman University of Pittsburgh at Pittsburgh Conflict of Interest Complexa, Inc. Value cannot be readily determined
Bruce Freeman University of Pittsburgh at Pittsburgh Conflict of Interest Complexa, Inc. Value cannot be readily determined
If you see an error in the database or a reason we should not disclose a record, please contact us at [email protected] and we'll evaluate it on a case-by-case basis.
Sources: National Institutes of Health, public records requests filed at multiple public state universities

Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.

Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.

ProPublica obtained additional financial disclosures and conflict of interest forms that we have not yet digitized and added to the database. You can download those disclosures in the ProPublica Data Store.

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