Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
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Lawrence Lum
University of Virginia, Department: Internal Medicine/medicine
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Transtarget, Inc (TTI)
Equity Interest - Non-publicly traded entity ( e.g., stock, stock option, or other ownership interest)
Dr. Lum owns substantial equity in Transtarget, Inc (TTI) which has licensed the technology which is the basis for this NIH project. While TTI is not a sponsor of this research and will not be a sub-contractor on any of this work, they may have access to the data under a data use agreement. The results of this study could effect the financial inerests of TTI.
Targeting Neuroblastoma with armed T cells
We will conduct a phase I/II dose escalation trial in high risk patients with neuroblastoma and other GD2+ pediatric tumors using activated T cells armed with anti-CD3 x humanized anti-GD2 bispecific antibody to determine safety and to determine whether infusions can improve clinical outcomes and induce both adaptive and innate immune responses in patients with high risk neuroblastoma. Immune correlates and exploratory PET/CT imaging studies will be performed to confirm immune responses and trafficking of the targeted T cells. If robust immune responses are obtained, these studies will provide a shift in the treatment paradigm for neuroblastoma where targeted T cells could be used in combination with 'best' treatment to further reduce disease and improve PFS and OS.
Filed on June 19, 2017.
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Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
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