Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
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Marc Breton
University of Virginia, Department: Psychiatry
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TypeZero Technologies, LLC
Equity Interest - Non-publicly traded entity ( e.g., stock, stock option, or other ownership interest)
Dr. Breton has equity in TypeZero Technologies, LLC which has licensed technology from UVa related to closed-loop control (artificial pancreas) in diabetes. The technologies to be developed in this project are not part of the TypeZero license, though they will be or may be derived from the base technology which was licensed to TypeZero.
Dr. Breton and the other participating engineers will be updating and modifying UVa technology for use in these experiments and other participating clinicians will be involved in testing these changes in the proposed clinical trials. Though this new technology has not been licensed (or promised) to TypeZero, it will likely be derived from the technology which was licensed to TypeZero. This formed the basis of our determination that this financial interest was related to this project.
Though the proposed experiments are not a test of licensed technology, the results of these experiments could effect the financial interests of TypeZero in the underlying technology, and given the participation of researchers with a financial interest this raised the possibility that this could effect the design, conduct or reporting of these proposed experiments.
Models, signals, and distributed bio-behavioral control of exercise in diabetes
The basic philosophy behind this project is simple: by using a hierarchical modular architecture, the exercise-informed Artificial Pancreas system is capable to adjust it functionalities to available devices and therefore can ensure optimal glycemic safety accounting for patients' device choices. As we escalate the use of devices (AP enabled platform, exercise sensors), new functionalities become available (closed loop glucose control, exercise-informed control), reducing hypoglycemic risk at different times around exercise: for example adding an exercise sensor to a sensor augmented pump (SAP) system limits the exposure to hypoglycemia during exercise (SAPEX), while enabling closed loop control limits hypoglycemia the night afterward (AP). This escalation culminates with an exercise-informed artificial pancreas system that combines the patient specific alert and advice system with AP technologies including exercise specific feedback control modules (APEX). We will demonstrate safety and efficacy of all these glucose control modes in three human clinical trials: two safety and feasibility studies of an exercise-informed decision support system and an exercise-informed automatic insulin modulation system respectively; and finally a long term (4 months) study where we will explore the efficacy of each AP mode.
Filed on July 11, 2016.
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Other search results for: “Marc Breton”
| Name | Institution | Type | Company | Disclosed Value |
|---|---|---|---|---|
| Marc Breton | University of Virginia | Conflict of Interest | TypeZero LLC | Value cannot be readily determined |
| Marc Breton | University of Virginia | Conflict of Interest | TypeZero Technologies, LLC | Value cannot be readily determined |
| Marc Breton | University of Virginia | Conflict of Interest | TypeZero Technologies, LLC | Value cannot be readily determined |
Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
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