Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
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Ethan Lee
Vanderbilt University, Department: Anatomy/cell Biology
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StemSynergy Therapeutics
Equity Interest - Non-publicly traded entity ( e.g., stock, stock option, or other ownership interest)
Vanderbilt is currently negotiating a potential licensing agreement with StemSynergy Therapeutics for the use of an antibody developed in Dr. Lee’s lab (patented by Vanderbilt). In the grant, Dr. Lee proposes to use the antibody as a tool (among others) to dissect the basic mechanism of action of the tumor suppressor, Adenomatous Polyposis Coli, in the Wnt signaling pathway.
Mechanism of Wnt signal transduction
Narrative: This proposal focuses on the mechanism of the Wnt signal transduction pathway, which plays important roles in development and human disease. Our currently funded work focuses on the link between the APC tumor suppressor, and Wnt coreceptors as well as the mechanism by which the XIAP E3 ligase regulates transcription of Wnt target genes. With MIRA funding, we now propose to reconstitute the ?-catenin destruction complex and, based on several genome-scale screens performed in my lab, pursue studies on Wnt coreceptor activation at the plasma membrane, regulation of Wnt coreceptor stability, and kinase regulation of Wnt nuclear transcription.
Filed on July 09, 2018.
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Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
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