Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
Should you be removed from our database? Contact us at [email protected]. Read more below.
David Holtzman
Washington University, Department: Neurology
Should you be removed from our database? Contact us at [email protected]. Read more below.
Denali Therapeutics
Other : IP Rights through awardee institution
Based on WU’s Research COI Policy and the Procedures for Determining and Managing Research Financial Conflicts of Interests, the CIRC determined Dr. Holtzman’s personal financial relationship with Denali Therapeutics creates a financial conflict of interest due to the following reasons:
• Dr. Holtzman’s personal financial relationship with Denali is directly related to the research because the research is evaluating a technology developed by him, which is anticipated to be licensed to Denali
• The research could directly benefit Denali
• Dr. Holtzman’s role as Principal Investigator could directly affect the research
Note that while the CIRC determined Dr. Holtzman has a financial conflict of interest, the following elements were determined to help offset the risks posed by the conflict:
• The research is basic in nature and in its early stages
• The research is unlikely to have an immediate and direct effect on the value of the entity
• Additionally, a plan has been developed to mitigate his financial conflict of interest, which is outlined below
Novel Strategies and Mechanisms to Target APOE and Alzheimer's Disease
Alzheimer's disease is a major public health problem with no treatments that delay, slow, or prevent the disease. In this application, we are determining if we can target the major genetic risk factor for Alzheimer's disease, APOE, to enable new approaches to develop novel treatments.
Filed on October 21, 2015.
Tell us what you know about David Holtzman's disclosure
We're still reporting about conflicts of interest. Is there something you'd like to tell us about this disclosure?
David Holtzman filed other conflict of interest disclosures with the NIH:
| Name | Institution | Type | Company | Disclosed Value |
|---|---|---|---|---|
| David Holtzman | Ut Southwestern Medical Center | Conflict of Interest | C2N Diagnostics | $20,000 - $39,999 |
| David Holtzman | Ut Southwestern Medical Center | Conflict of Interest | C2N Diagnostics | Value cannot be readily determined |
| David Holtzman | Ut Southwestern Medical Center | Conflict of Interest | C2N Diagnostics | Value cannot be readily determined |
| David Holtzman | Ut Southwestern Medical Center | Conflict of Interest | C2N Diagnostics | Value cannot be readily determined |
Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
ProPublica obtained additional financial disclosures and conflict of interest forms that we have not yet digitized and added to the database. You can download those disclosures in the ProPublica Data Store.