Dollars for Profs

Dig Into University Researchers' Outside Income and Conflicts of Interest

Published Dec. 6, 2019

This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.

Financial doc
Filing Type

Conflict of Interest

Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.

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Samuel Wickline

Washington University, Department: Internal Medicine/medicine

Should you be removed from our database? Contact us at [email protected]. Read more below.

Disclosed Conflict of Interest with

Trasir Therapeutics

Disclosed Value
Listed Reason
Intellectual property rights (e.g., royalties, patents, copyrights) not from the awardee Institution

Based on Washington University’s (WU) Research COI Policy and the Procedures for Determining and Managing Research Financial Conflicts of Interests, WU determined Dr. Wickline's personal financial relationship with Trasir Therapeutics, related to the above referenced research creates a financial conflict of interest due to the following reasons:

•Dr. Wickline's personal financial relationship is directly related to the study because the studies are utilizing and evaluating his Intellectual Property, “Modified peptide that can deliver siRNA in vivo and in vitro”, which is licensed by Trasir Therapeutics.

•Dr. Wickline's role as the PI of the study, in designing the study, collecting and analyzing data, reporting the results, oversight of the research, supervising individuals involved with the research, and mentor could directly affect the outcome of the study

While the CIRC determined a financial conflict of interest exists, it concluded there are mitigating factors that help address the situation:

•The research is basic in nature and in its early phases.

•Dr. Wickline is uniquely qualified by virtue of his expertise and experience, and the research could not be conducted as effectively without his involvement.

•Additionally, a plan has been developed to address his financial conflict of interest, which is outlined below.

Listed Research Project
ANTI-INFLAMMATORY THERAPEUTICS FOR CARDIOVASCULAR DISEASE

Inflammation in atherosclerotic plaque is a key promoter of acute vascular syndromes (i.e., thrombosis). The theme of this proposal is the development and testing of nanoparticle based approaches for the diagnosis and therapy of cardiovascular diseases to detect, treat, and monitor unstable atheroma. We seek to develop new molecularly targeted nanotherapies that interrupt inflammatory signaling molecules with the clinical goal of reducing the propensity toward thrombosis in acute vascular syndromes. These will be tested in vivo in mouse models as single agent and combination therapies.

Filed on March 02, 2015.

Tell us what you know about Samuel Wickline's disclosure

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Name Institution Type Company Disclosed Value
Samuel Wickline Washington University Conflict of Interest Acuplaq Inc. $0 - $4,999
Samuel Wickline Washington University Conflict of Interest Entropy Vision, LLC $0 - $4,999
Samuel Wickline Washington University Conflict of Interest Acuplaq, Inc. $0 - $4,999
Samuel Wickline University of South Florida Conflict of Interest Trasir Therapeutics Value cannot be readily determined
Samuel Wickline Washington University Conflict of Interest Acuplaq, Inc. Value cannot be readily determined
Samuel Wickline Washington University Conflict of Interest Trasir Therapeutics Value cannot be readily determined
Samuel Wickline Washington University Conflict of Interest Acuplaq Inc. Value cannot be readily determined
Samuel Wickline Washington University Conflict of Interest Acuplaq Inc. Value cannot be readily determined
Samuel Wickline Washington University Conflict of Interest Trasir Therapeutics Value cannot be readily determined
Samuel Wickline Washington University Conflict of Interest Trasir Therapeutics Value cannot be readily determined
Samuel Wickline Washington University Conflict of Interest Trasir Therapeutics Value cannot be readily determined
Samuel Wickline Washington University Conflict of Interest Acuplaq, Inc. Value cannot be readily determined
Samuel Wickline Washington University Conflict of Interest Entropy Vision, LLC Value cannot be readily determined
Samuel Wickline University of South Florida Conflict of Interest Trasir Therapeutics Value cannot be readily determined
Samuel Wickline Washington University Conflict of Interest Trasir Therapeutics Value cannot be readily determined
Samuel Wickline University of South Florida Conflict of Interest AcuPlaq, LLC Value cannot be readily determined
Samuel Wickline Washington University Conflict of Interest Trasir Therapeutics Value cannot be readily determined
Samuel Wickline University of South Florida Conflict of Interest AcuPlaq, LLC Value cannot be readily determined
If you see an error in the database or a reason we should not disclose a record, please contact us at [email protected] and we'll evaluate it on a case-by-case basis.
Sources: National Institutes of Health, public records requests filed at multiple public state universities

Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.

Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.

ProPublica obtained additional financial disclosures and conflict of interest forms that we have not yet digitized and added to the database. You can download those disclosures in the ProPublica Data Store.

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