Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
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Donald Engelman
Yale University, Department: Radiation Diagnostic/oncology
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pHLIP, Inc.
Equity Interest - Non-publicly traded entity ( e.g., stock, stock option, or other ownership interest)
Please refer to the attached document for the required information.
Novel DNA Repair Inhibitors for Cancer Therapy
Project Narrative. We seek to identify novel therapeutic agents that are selectively toxic to cancer cells and that specifically sensitize tumors to radiation or chemotherapy. We have discovered that a lupus-derived, cell-penetrating autoantibody (3E10) inhibits DNA repair and can increase the sensitivity of cancer cells to radiation and chemotherapy but is otherwise non-toxic to human cells. We have also developed novel peptide conjugates that selectively target tumors and spare normal tissues, and we will use these to deliver specific DNA repair inhibitors to cancer cells. We will investigate the mechanism of action of these agents and elucidate how they can best be used for cancer therapy.
Filed on August 31, 2017.
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Other search results for: “Donald Engelman”
| Name | Institution | Type | Company | Disclosed Value |
|---|---|---|---|---|
| Donald Engelman | Yale University | Conflict of Interest | pHLIP, Inc. | Value cannot be readily determined |
| Donald Engelman | Yale University | Conflict of Interest | pHLIP, Inc. | Value cannot be readily determined |
| Donald Engelman | Yale University | Conflict of Interest | pHLIP, Inc. | Value cannot be readily determined |
Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
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