Dollars for Profs
Dig Into University Researchers' Outside Income and Conflicts of Interest
Published Dec. 6, 2019
This database was last updated in December 2019 and should only be used as a historical snapshot. There may be new or amended records not reflected here.
Conflict of Interest
Institutions must file significant disclosures to the National Institutes of Health if they determine financial relationships could affect the design, conduct or reporting of the NIH-funded research. The NIH provided us with their entire financial conflict of interest database, with filings from 2012 through 2019.
Should you be removed from our database? Contact us at [email protected]. Read more below.
Oleg Andreev
Yale University, Department: Biochemistry
Should you be removed from our database? Contact us at [email protected]. Read more below.
pHLIP, Inc.
Equity Interest - Non-publicly traded entity ( e.g., stock, stock option, or other ownership interest)
Please see the attached document for the required information.
Mechanism and Uses of Transmembrane Helix Insertion by Soluble Peptides
As a result of earlier funding by the NIH, we have discovered a family of peptides, called 'pHLIPs', that (1) target acidic tissues in vivo, including tumors, an (2) can deliver therapeutic polar molecules into cells, releasing them in the cytoplasm. Our recent studies have shown effective targeted delivery of a therapeutic molecule that dramatically suppresses lymphoma, including metastases, in a mouse model. Our work on the pHLIP peptides has led to new insights about the basic science of peptide insertion into membranes in terms of structure, energetics and kinetics, and as we learn more about the principles, we will be able to design better versions of peptides for specific clinical applications.
Filed on February 22, 2016.
Tell us what you know about Oleg Andreev's disclosure
We're still reporting about conflicts of interest. Is there something you'd like to tell us about this disclosure?
Notes: When a more specific filing date is not available for an individual financial disclosure or conflict of interest form, we use the year the form was filed. If the year was not disclosed, we report the range of years covered by our public records requests. In a few cases, a start date was provided instead of a filing date. In those cases, we use the start date instead.
Fewer than 10% of records from the University of Florida and fewer than 1% of records from the University of Texas system were removed because they did not contain enough information.
ProPublica obtained additional financial disclosures and conflict of interest forms that we have not yet digitized and added to the database. You can download those disclosures in the ProPublica Data Store.